Lan Y - Search Results

1

NHS-IL12 and bintrafusp alfa combination therapy enhances antitumor activity in preclinical cancer models.

Xu C, Marelli B, Qi J, Qin G, Yu H, Wang H, Jenkins MH, Lo KM, Lan Y. Xu C, et al. Among authors: lan y. Transl Oncol. 2022 Feb;16:101322. doi: 10.1016/j.tranon.2021.101322. Epub 2021 Dec 23. Transl Oncol. 2022. PMID: 34954456 Free PMC article.

2

Improved circulating half-life and efficacy of an antibody-interleukin 2 immunocytokine based on reduced intracellular proteolysis.

Gillies SD, Lo KM, Burger C, Lan Y, Dahl T, Wong WK. Gillies SD, et al. Among authors: lan y. Clin Cancer Res. 2002 Jan;8(1):210-6. Clin Cancer Res. 2002. PMID: 11801561

3

Bi-functional cytokine fusion proteins for gene therapy and antibody-targeted treatment of cancer.

Gillies SD, Lan Y, Brunkhorst B, Wong WK, Li Y, Lo KM. Gillies SD, et al. Among authors: lan y. Cancer Immunol Immunother. 2002 Oct;51(8):449-60. doi: 10.1007/s00262-002-0302-6. Epub 2002 Jul 12. Cancer Immunol Immunother. 2002. PMID: 12202906 Free PMC article.

4

An anti-CD20-IL-2 immunocytokine is highly efficacious in a SCID mouse model of established human B lymphoma.

Gillies SD, Lan Y, Williams S, Carr F, Forman S, Raubitschek A, Lo KM. Gillies SD, et al. Among authors: lan y. Blood. 2005 May 15;105(10):3972-8. doi: 10.1182/blood-2004-09-3533. Epub 2005 Feb 3. Blood. 2005. PMID: 15692062 Free article.

5

Engineering a pharmacologically superior form of leptin for the treatment of obesity.

Lo KM, Zhang J, Sun Y, Morelli B, Lan Y, Lauder S, Brunkhorst B, Webster G, Hallakou-Bozec S, Doaré L, Gillies SD. Lo KM, et al. Among authors: lan y. Protein Eng Des Sel. 2005 Jan;18(1):1-10. doi: 10.1093/protein/gzh102. Protein Eng Des Sel. 2005. PMID: 15790575

6

Improvement of Fc-erythropoietin structure and pharmacokinetics by modification at a disulfide bond.

Way JC, Lauder S, Brunkhorst B, Kong SM, Qi A, Webster G, Campbell I, McKenzie S, Lan Y, Marelli B, Nguyen LA, Degon S, Lo KM, Gillies SD. Way JC, et al. Among authors: lan y. Protein Eng Des Sel. 2005 Mar;18(3):111-8. doi: 10.1093/protein/gzi021. Epub 2005 Apr 8. Protein Eng Des Sel. 2005. PMID: 15820978

7

huBC1-IL12, an immunocytokine which targets EDB-containing oncofetal fibronectin in tumors and tumor vasculature, shows potent anti-tumor activity in human tumor models.

Lo KM, Lan Y, Lauder S, Zhang J, Brunkhorst B, Qin G, Verma R, Courtenay-Luck N, Gillies SD. Lo KM, et al. Among authors: lan y. Cancer Immunol Immunother. 2007 Apr;56(4):447-57. doi: 10.1007/s00262-006-0203-1. Epub 2006 Jul 28. Cancer Immunol Immunother. 2007. PMID: 16874486 Free PMC article.

8

SEEDbodies: fusion proteins based on strand-exchange engineered domain (SEED) CH3 heterodimers in an Fc analogue platform for asymmetric binders or immunofusions and bispecific antibodies.

Davis JH, Aperlo C, Li Y, Kurosawa E, Lan Y, Lo KM, Huston JS. Davis JH, et al. Among authors: lan y. Protein Eng Des Sel. 2010 Apr;23(4):195-202. doi: 10.1093/protein/gzp094. Epub 2010 Feb 4. Protein Eng Des Sel. 2010. PMID: 20299542

9

A low-toxicity IL-2-based immunocytokine retains antitumor activity despite its high degree of IL-2 receptor selectivity.

Gillies SD, Lan Y, Hettmann T, Brunkhorst B, Sun Y, Mueller SO, Lo KM. Gillies SD, et al. Among authors: lan y. Clin Cancer Res. 2011 Jun 1;17(11):3673-85. doi: 10.1158/1078-0432.CCR-10-2921. Epub 2011 Apr 29. Clin Cancer Res. 2011. PMID: 21531812

10

Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans.

Waight JD, Takai S, Marelli B, Qin G, Hance KW, Zhang D, Tighe R, Lan Y, Lo KM, Sabzevari H, Hofmeister R, Wilson NS. Waight JD, et al. Among authors: lan y. J Immunol. 2015 Feb 1;194(3):878-82. doi: 10.4049/jimmunol.1402725. Epub 2014 Dec 29. J Immunol. 2015. PMID: 25548231 Free PMC article.

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