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Development and validation of a radiopathomics model to predict pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicentre observational study.
Feng L, Liu Z, Li C, Li Z, Lou X, Shao L, Wang Y, Huang Y, Chen H, Pang X, Liu S, He F, Zheng J, Meng X, Xie P, Yang G, Ding Y, Wei M, Yun J, Hung MC, Zhou W, Wahl DR, Lan P, Tian J, Wan X. Feng L, et al. Among authors: wahl dr. Lancet Digit Health. 2022 Jan;4(1):e8-e17. doi: 10.1016/S2589-7500(21)00215-6. Lancet Digit Health. 2022. PMID: 34952679 Free article.
MRNIP condensates promote DNA double-strand break sensing and end resection.
Wang YL, Zhao WW, Bai SM, Feng LL, Bie SY, Gong L, Wang F, Wei MB, Feng WX, Pang XL, Qin CL, Yin XK, Wang YN, Zhou W, Wahl DR, Liu Q, Chen M, Hung MC, Wan XB. Wang YL, et al. Among authors: wahl dr. Nat Commun. 2022 May 12;13(1):2638. doi: 10.1038/s41467-022-30303-w. Nat Commun. 2022. PMID: 35551189 Free PMC article.
Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Umemura Y, Orringer D, Junck L, Varela ML, West MEJ, Faisal SM, Comba A, Heth J, Sagher O, Leung D, Mammoser A, Hervey-Jumper S, Zamler D, Yadav VN, Dunn P, Al-Holou W, Hollon T, Kim MM, Wahl DR, Camelo-Piragua S, Lieberman AP, Venneti S, McKeever P, Lawrence T, Kurokawa R, Sagher K, Altshuler D, Zhao L, Muraszko K, Castro MG, Lowenstein PR. Umemura Y, et al. Among authors: wahl dr. Lancet Oncol. 2023 Sep;24(9):1042-1052. doi: 10.1016/S1470-2045(23)00347-9. Lancet Oncol. 2023. PMID: 37657463 Clinical Trial.
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma.
Zhou W, Yao Y, Scott AJ, Wilder-Romans K, Dresser JJ, Werner CK, Sun H, Pratt D, Sajjakulnukit P, Zhao SG, Davis M, Nelson BS, Halbrook CJ, Zhang L, Gatto F, Umemura Y, Walker AK, Kachman M, Sarkaria JN, Xiong J, Morgan MA, Rehemtualla A, Castro MG, Lowenstein P, Chandrasekaran S, Lawrence TS, Lyssiotis CA, Wahl DR. Zhou W, et al. Among authors: wahl dr. Nat Commun. 2020 Jul 30;11(1):3811. doi: 10.1038/s41467-020-17512-x. Nat Commun. 2020. PMID: 32732914 Free PMC article.
Adaptive rewiring of purine metabolism promotes treatment resistance in H3K27M-mutant diffuse midline glioma.
Peterson ER, Sajjakulnukit P, Scott AJ, Heaslip C, Andren A, Wilder-Romans K, Zhou W, Palavalasa S, Korimerla N, Lin A, Obrien A, Kothari A, Zhao Z, Zhang L, Morgan MA, Venneti S, Koschmann C, Jabado N, Lyssiotis CA, Castro MG, Wahl DR. Peterson ER, et al. Among authors: wahl dr. Res Sq [Preprint]. 2023 Sep 11:rs.3.rs-3317816. doi: 10.21203/rs.3.rs-3317816/v1. Res Sq. 2023. Update in: Cancer Metab. 2024 Apr 9;12(1):11. doi: 10.1186/s40170-024-00341-7 PMID: 37790517 Free PMC article. Updated. Preprint.
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