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Page 1
HuR-targeted agents: An insight into medicinal chemistry, biophysical, computational studies and pharmacological effects on cancer models.
Assoni G, La Pietra V, Digilio R, Ciani C, Licata NV, Micaelli M, Facen E, Tomaszewska W, Cerofolini L, Pérez-Ràfols A, Varela Rey M, Fragai M, Woodhoo A, Marinelli L, Arosio D, Bonomo I, Provenzani A, Seneci P. Assoni G, et al. Among authors: perez rafols a. Adv Drug Deliv Rev. 2022 Feb;181:114088. doi: 10.1016/j.addr.2021.114088. Epub 2021 Dec 20. Adv Drug Deliv Rev. 2022. PMID: 34942276 Review.
VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Lange SM, McFarland MR, Lamoliatte F, Carroll T, Krshnan L, Pérez-Ràfols A, Kwasna D, Shen L, Wallace I, Cole I, Armstrong LA, Knebel A, Johnson C, De Cesare V, Kulathu Y. Lange SM, et al. Among authors: perez rafols a. Nat Struct Mol Biol. 2024 Dec;31(12):1872-1887. doi: 10.1038/s41594-024-01354-y. Epub 2024 Jul 8. Nat Struct Mol Biol. 2024. PMID: 38977901 Free PMC article.
Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria.
Dolcemascolo R, Heras-Hernández M, Goiriz L, Montagud-Martínez R, Requena-Menéndez A, Ruiz R, Pérez-Ràfols A, Higuera-Rodríguez RA, Pérez-Ropero G, Vranken WF, Martelli T, Kaiser W, Buijs J, Rodrigo G. Dolcemascolo R, et al. Among authors: perez rafols a. Elife. 2024 Feb 16;12:RP91777. doi: 10.7554/eLife.91777. Elife. 2024. PMID: 38363283 Free PMC article.
Experiences with a training DSW knowledge model for early-stage researchers.
Devignes MD, Smaïl-Tabbone M, Dhondge H, Dolcemascolo R, Gavaldá-García J, Higuera-Rodriguez RA, Kravchenko A, Roca Martínez J, Messini N, Pérez-Ràfols A, Pérez Ropero G, Sperotto L, Chauvot de Beauchêne I, Vranken W. Devignes MD, et al. Among authors: perez rafols a. Open Res Eur. 2023 Jun 19;3:97. doi: 10.12688/openreseurope.15609.1. eCollection 2023. Open Res Eur. 2023. PMID: 37645489 Free PMC article.
Combining Solid-State NMR with Structural and Biophysical Techniques to Design Challenging Protein-Drug Conjugates.
Cerofolini L, Vasa K, Bianconi E, Salobehaj M, Cappelli G, Bonciani A, Licciardi G, Pérez-Ràfols A, Padilla-Cortés L, Antonacci S, Rizzo D, Ravera E, Viglianisi C, Calderone V, Parigi G, Luchinat C, Macchiarulo A, Menichetti S, Fragai M. Cerofolini L, et al. Among authors: perez rafols a. Angew Chem Int Ed Engl. 2023 Aug 1;62(31):e202303202. doi: 10.1002/anie.202303202. Epub 2023 Jun 22. Angew Chem Int Ed Engl. 2023. PMID: 37276329
HuR modulation counteracts lipopolysaccharide response in murine macrophages.
Bonomo I, Assoni G, La Pietra V, Canarutto G, Facen E, Donati G, Zucal C, Genovese S, Micaelli M, Pérez-Ràfols A, Robbiati S, Kontoyannis DL, De Matteo M, Fragai M, Seneci P, Marinelli L, Arosio D, Piazza S, Provenzani A. Bonomo I, et al. Among authors: perez rafols a. Dis Model Mech. 2023 Mar 1;16(3):dmm050120. doi: 10.1242/dmm.050120. Epub 2023 Mar 29. Dis Model Mech. 2023. PMID: 36912171 Free PMC article.