Thomann M - Search Results

1

Implementation of in vitro glycoengineering of monoclonal antibodies into downstream processing of industrial production.

Malik S, Grunert I, von Roman MF, Walch H, Dams T, Thomann M, Falkenstein R. Malik S, et al. Among authors: thomann m. Glycobiology. 2022 Mar 19;32(2):123-135. doi: 10.1093/glycob/cwab109. Glycobiology. 2022. PMID: 34939096

2

In vitro glycoengineering of IgG1 and its effect on Fc receptor binding and ADCC activity.

Thomann M, Schlothauer T, Dashivets T, Malik S, Avenal C, Bulau P, Rüger P, Reusch D. Thomann M, et al. PLoS One. 2015 Aug 12;10(8):e0134949. doi: 10.1371/journal.pone.0134949. eCollection 2015. PLoS One. 2015. PMID: 26266936 Free PMC article.

3

Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants.

Dashivets T, Thomann M, Rueger P, Knaupp A, Buchner J, Schlothauer T. Dashivets T, et al. Among authors: thomann m. PLoS One. 2015 Dec 11;10(12):e0143520. doi: 10.1371/journal.pone.0143520. eCollection 2015. PLoS One. 2015. PMID: 26657484 Free PMC article.

4

Fc-galactosylation modulates antibody-dependent cellular cytotoxicity of therapeutic antibodies.

Thomann M, Reckermann K, Reusch D, Prasser J, Tejada ML. Thomann M, et al. Mol Immunol. 2016 May;73:69-75. doi: 10.1016/j.molimm.2016.03.002. Epub 2016 Apr 6. Mol Immunol. 2016. PMID: 27058641 Free article.

5

Two N-terminally truncated variants of human β-galactoside α2,6 sialyltransferase I with distinct properties for in vitro protein glycosylation.

Luley-Goedl C, Schmoelzer K, Thomann M, Malik S, Greif M, Ribitsch D, Jung C, Sobek H, Engel A, Mueller R, Schwab H, Nidetzky B. Luley-Goedl C, et al. Among authors: thomann m. Glycobiology. 2016 Oct;26(10):1097-1106. doi: 10.1093/glycob/cww046. Epub 2016 Apr 21. Glycobiology. 2016. PMID: 27102286

6

Effects of sialic acid linkage on antibody-fragment crystallizable receptor binding and antibody dependent cytotoxicity depend on levels of fucosylation/bisecting.

Thomann M, Malik S, Kuhne F, Avenal C, Plath F, Bonnington L, Reusch D, Bulau P, Cymer F. Thomann M, et al. Bioanalysis. 2019 Aug;11(15):1437-1449. doi: 10.4155/bio-2019-0124. Bioanalysis. 2019. PMID: 31490109

7

The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange.

Kuhne F, Bonnington L, Malik S, Thomann M, Avenal C, Cymer F, Wegele H, Reusch D, Mormann M, Bulau P. Kuhne F, et al. Among authors: thomann m. Antibodies (Basel). 2019 Oct 1;8(4):49. doi: 10.3390/antib8040049. Antibodies (Basel). 2019. PMID: 31581521 Free PMC article.

8

Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach.

Hajduk J, Brunner C, Malik S, Bangerter J, Schneider G, Thomann M, Reusch D, Zenobi R. Hajduk J, et al. Among authors: thomann m. MAbs. 2020 Jan-Dec;12(1):1736975. doi: 10.1080/19420862.2020.1736975. MAbs. 2020. PMID: 32167012 Free PMC article.

9

Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody.

Falck D, Thomann M, Lechmann M, Koeleman CAM, Malik S, Jany C, Wuhrer M, Reusch D. Falck D, et al. Among authors: thomann m. MAbs. 2021 Jan-Dec;13(1):1865596. doi: 10.1080/19420862.2020.1865596. MAbs. 2021. PMID: 33382957 Free PMC article.

10

Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model.

Falck D, Lechmann M, Momčilović A, Thomann M, Koeleman CAM, Jany C, Malik S, Wuhrer M, Reusch D. Falck D, et al. Among authors: thomann m. MAbs. 2022 Jan-Dec;14(1):2145929. doi: 10.1080/19420862.2022.2145929. MAbs. 2022. PMID: 36383465 Free PMC article.

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