Meek K - Search Results

1

Autophosphorylation transforms DNA-PK from protecting to processing DNA ends.

Liu L, Chen X, Li J, Wang H, Buehl CJ, Goff NJ, Meek K, Yang W, Gellert M. Liu L, et al. Among authors: meek k. Mol Cell. 2022 Jan 6;82(1):177-189.e4. doi: 10.1016/j.molcel.2021.11.025. Epub 2021 Dec 21. Mol Cell. 2022. PMID: 34936881 Free PMC article.

2

DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties.

Liu L, Kwak YT, Bex F, García-Martínez LF, Li XH, Meek K, Lane WS, Gaynor RB. Liu L, et al. Among authors: meek k. Mol Cell Biol. 1998 Jul;18(7):4221-34. doi: 10.1128/MCB.18.7.4221. Mol Cell Biol. 1998. PMID: 9632806 Free PMC article.

3

Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination.

Kienker LJ, Shin EK, Meek K. Kienker LJ, et al. Among authors: meek k. Nucleic Acids Res. 2000 Jul 15;28(14):2752-61. doi: 10.1093/nar/28.14.2752. Nucleic Acids Res. 2000. PMID: 10908332 Free PMC article.

4

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.

Ding Q, Reddy YV, Wang W, Woods T, Douglas P, Ramsden DA, Lees-Miller SP, Meek K. Ding Q, et al. Among authors: meek k. Mol Cell Biol. 2003 Aug;23(16):5836-48. doi: 10.1128/MCB.23.16.5836-5848.2003. Mol Cell Biol. 2003. PMID: 12897153 Free PMC article.

5

The DNA-dependent protein kinase: the director at the end.

Meek K, Gupta S, Ramsden DA, Lees-Miller SP. Meek K, et al. Immunol Rev. 2004 Aug;200:132-41. doi: 10.1111/j.0105-2896.2004.00162.x. Immunol Rev. 2004. PMID: 15242401 Review.

6

Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice.

Cui X, Yu Y, Gupta S, Cho YM, Lees-Miller SP, Meek K. Cui X, et al. Among authors: meek k. Mol Cell Biol. 2005 Dec;25(24):10842-52. doi: 10.1128/MCB.25.24.10842-10852.2005. Mol Cell Biol. 2005. PMID: 16314509 Free PMC article.

7

The leucine rich region of DNA-PKcs contributes to its innate DNA affinity.

Gupta S, Meek K. Gupta S, et al. Among authors: meek k. Nucleic Acids Res. 2005 Dec 9;33(22):6972-81. doi: 10.1093/nar/gki990. Print 2005. Nucleic Acids Res. 2005. PMID: 16340007 Free PMC article.

8

trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining.

Meek K, Douglas P, Cui X, Ding Q, Lees-Miller SP. Meek K, et al. Mol Cell Biol. 2007 May;27(10):3881-90. doi: 10.1128/MCB.02366-06. Epub 2007 Mar 12. Mol Cell Biol. 2007. PMID: 17353268 Free PMC article.

9

Linking double-stranded DNA breaks to the recombination activating gene complex directs repair to the nonhomologous end-joining pathway.

Cui X, Meek K. Cui X, et al. Among authors: meek k. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17046-51. doi: 10.1073/pnas.0610928104. Epub 2007 Oct 15. Proc Natl Acad Sci U S A. 2007. PMID: 17939999 Free PMC article.

10

DNA-PK: the means to justify the ends?

Meek K, Dang V, Lees-Miller SP. Meek K, et al. Adv Immunol. 2008;99:33-58. doi: 10.1016/S0065-2776(08)00602-0. Adv Immunol. 2008. PMID: 19117531 Review.

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