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Challenges and Opportunities for Nucleic Acid Therapeutics.
Corey DR, Damha MJ, Manoharan M. Corey DR, et al. Among authors: manoharan m. Nucleic Acid Ther. 2022 Feb;32(1):8-13. doi: 10.1089/nat.2021.0085. Epub 2021 Dec 17. Nucleic Acid Ther. 2022. PMID: 34931905 Free PMC article.
RNAi-mediated gene silencing in non-human primates.
Zimmermann TS, Lee AC, Akinc A, Bramlage B, Bumcrot D, Fedoruk MN, Harborth J, Heyes JA, Jeffs LB, John M, Judge AD, Lam K, McClintock K, Nechev LV, Palmer LR, Racie T, Röhl I, Seiffert S, Shanmugam S, Sood V, Soutschek J, Toudjarska I, Wheat AJ, Yaworski E, Zedalis W, Koteliansky V, Manoharan M, Vornlocher HP, MacLachlan I. Zimmermann TS, et al. Among authors: manoharan m. Nature. 2006 May 4;441(7089):111-4. doi: 10.1038/nature04688. Epub 2006 Mar 26. Nature. 2006. PMID: 16565705
Modulation of thermal stability can enhance the potency of siRNA.
Addepalli H, Meena, Peng CG, Wang G, Fan Y, Charisse K, Jayaprakash KN, Rajeev KG, Pandey RK, Lavine G, Zhang L, Jahn-Hofmann K, Hadwiger P, Manoharan M, Maier MA. Addepalli H, et al. Among authors: manoharan m. Nucleic Acids Res. 2010 Nov;38(20):7320-31. doi: 10.1093/nar/gkq568. Epub 2010 Jul 7. Nucleic Acids Res. 2010. PMID: 20610434 Free PMC article.
Promoter RNA links transcriptional regulation of inflammatory pathway genes.
Matsui M, Chu Y, Zhang H, Gagnon KT, Shaikh S, Kuchimanchi S, Manoharan M, Corey DR, Janowski BA. Matsui M, et al. Among authors: manoharan m. Nucleic Acids Res. 2013 Dec;41(22):10086-109. doi: 10.1093/nar/gkt777. Epub 2013 Sep 2. Nucleic Acids Res. 2013. PMID: 23999091 Free PMC article.
536 results