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Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development.
Mai E, Chan J, Goon L, Ego BK, Bevers J, Wong T, Wong M, Corpuz R, Xi H, Wu J, Schneider K, Seshasayee D, Grimbaldeston M, Nakamura G, Indjeian VB, van Lookeren Campagne M, Loyet KM, Comps-Agrar L. Mai E, et al. Among authors: nakamura g. J Transl Med. 2021 Dec 20;19(1):517. doi: 10.1186/s12967-021-03189-3. J Transl Med. 2021. PMID: 34930320 Free PMC article.
Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines.
Spiess C, Bevers J 3rd, Jackman J, Chiang N, Nakamura G, Dillon M, Liu H, Molina P, Elliott JM, Shatz W, Scheer JM, Giese G, Persson J, Zhang Y, Dennis MS, Giulianotti J, Gupta P, Reilly D, Palma E, Wang J, Stefanich E, Scheerens H, Fuh G, Wu LC. Spiess C, et al. Among authors: nakamura g. J Biol Chem. 2013 Sep 13;288(37):26583-93. doi: 10.1074/jbc.M113.480483. Epub 2013 Jul 23. J Biol Chem. 2013. PMID: 23880771 Free PMC article.
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal.
Storek KM, Auerbach MR, Shi H, Garcia NK, Sun D, Nickerson NN, Vij R, Lin Z, Chiang N, Schneider K, Wecksler AT, Skippington E, Nakamura G, Seshasayee D, Koerber JT, Payandeh J, Smith PA, Rutherford ST. Storek KM, et al. Among authors: nakamura g. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3692-3697. doi: 10.1073/pnas.1800043115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555747 Free PMC article.
A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies.
Vij R, Lin Z, Chiang N, Vernes JM, Storek KM, Park S, Chan J, Meng YG, Comps-Agrar L, Luan P, Lee S, Schneider K, Bevers J 3rd, Zilberleyb I, Tam C, Koth CM, Xu M, Gill A, Auerbach MR, Smith PA, Rutherford ST, Nakamura G, Seshasayee D, Payandeh J, Koerber JT. Vij R, et al. Among authors: nakamura g. Sci Rep. 2018 May 8;8(1):7136. doi: 10.1038/s41598-018-25609-z. Sci Rep. 2018. PMID: 29740124 Free PMC article.
Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD.
Storek KM, Chan J, Vij R, Chiang N, Lin Z, Bevers J 3rd, Koth CM, Vernes JM, Meng YG, Yin J, Wallweber H, Dalmas O, Shriver S, Tam C, Schneider K, Seshasayee D, Nakamura G, Smith PA, Payandeh J, Koerber JT, Comps-Agrar L, Rutherford ST. Storek KM, et al. Among authors: nakamura g. Elife. 2019 Jun 25;8:e46258. doi: 10.7554/eLife.46258. Elife. 2019. PMID: 31237236 Free PMC article.
Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate.
Kajihara KK, Pantua H, Hernandez-Barry H, Hazen M, Deshmukh K, Chiang N, Ohri R, Castellanos ER, Martin L, Matsumoto ML, Payandeh J, Storek KM, Schneider K, Smith PA, Koehler MFT, Tsai SP, Vandlen R, Loyet KM, Nakamura G, Pillow T, Seshasayee D, Kapadia SB, Hazenbos WLW. Kajihara KK, et al. Among authors: nakamura g. mBio. 2021 Jun 29;12(3):e0020221. doi: 10.1128/mBio.00202-21. Epub 2021 Jun 1. mBio. 2021. PMID: 34061593 Free PMC article.
An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases.
Xie MM, Dai B, Hackney JA, Sun T, Zhang J, Jackman JK, Jeet S, Irizarry-Caro RA, Fu Y, Liang Y, Bender H, Shamir ER, Keir ME, Bevers J, Nakamura G, Townsend MJ, Fox DA, Scherl A, Lee WP, Martin F, Godowski PJ, Pappu R, Yi T. Xie MM, et al. Among authors: nakamura g. Cell Rep Med. 2023 Aug 15;4(8):101130. doi: 10.1016/j.xcrm.2023.101130. Epub 2023 Jul 24. Cell Rep Med. 2023. PMID: 37490914 Free PMC article.
272 results