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Page 1
VLDLR and ApoER2 are receptors for multiple alphaviruses.
Clark LE, Clark SA, Lin C, Liu J, Coscia A, Nabel KG, Yang P, Neel DV, Lee H, Brusic V, Stryapunina I, Plante KS, Ahmed AA, Catteruccia F, Young-Pearse TL, Chiu IM, Llopis PM, Weaver SC, Abraham J. Clark LE, et al. Among authors: clark sa. Nature. 2022 Feb;602(7897):475-480. doi: 10.1038/s41586-021-04326-0. Epub 2021 Dec 20. Nature. 2022. PMID: 34929721 Free PMC article.
Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4. Epub 2021 Jun 24. Nat Chem Biol. 2021. PMID: 34168368 Free PMC article.
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain.
Nabel KG, Clark SA, Shankar S, Pan J, Clark LE, Yang P, Coscia A, McKay LGA, Varnum HH, Brusic V, Tolan NV, Zhou G, Desjardins M, Turbett SE, Kanjilal S, Sherman AC, Dighe A, LaRocque RC, Ryan ET, Tylek C, Cohen-Solal JF, Darcy AT, Tavella D, Clabbers A, Fan Y, Griffiths A, Correia IR, Seagal J, Baden LR, Charles RC, Abraham J. Nabel KG, et al. Among authors: clark le, clark sa. Science. 2022 Jan 21;375(6578):eabl6251. doi: 10.1126/science.abl6251. Epub 2022 Jan 21. Science. 2022. PMID: 34855508 Free PMC article.
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J. Junqueira C, et al. Nature. 2022 Jun;606(7914):576-584. doi: 10.1038/s41586-022-04702-4. Epub 2022 Apr 6. Nature. 2022. PMID: 35385861 Free PMC article.
Structural basis for VLDLR recognition by eastern equine encephalitis virus.
Yang P, Li W, Fan X, Pan J, Mann CJ, Varnum H, Clark LE, Clark SA, Coscia A, Smith KN, Brusic V, Abraham J. Yang P, et al. Among authors: clark le, clark sa. bioRxiv [Preprint]. 2023 Nov 14:2023.11.14.567065. doi: 10.1101/2023.11.14.567065. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 2;15(1):6548. doi: 10.1038/s41467-024-50887-9 PMID: 38014066 Free PMC article. Updated. Preprint.
Structural basis for VLDLR recognition by eastern equine encephalitis virus.
Yang P, Li W, Fan X, Pan J, Mann CJ, Varnum H, Clark LE, Clark SA, Coscia A, Basu H, Smith KN, Brusic V, Abraham J. Yang P, et al. Among authors: clark le, clark sa. Nat Commun. 2024 Aug 2;15(1):6548. doi: 10.1038/s41467-024-50887-9. Nat Commun. 2024. PMID: 39095394 Free PMC article.
SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release.
Junqueira C, Crespo Â, Ranjbar S, Lewandrowski M, Ingber J, de Lacerda LB, Parry B, Ravid S, Clark S, Ho F, Vora SM, Leger V, Beakes C, Margolin J, Russell N, Kays K, Gehrke L, Adhikari UD, Henderson L, Janssen E, Kwon D, Sander C, Abraham J, Filbin M, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Lieberman J. Junqueira C, et al. Res Sq [Preprint]. 2021 Aug 11:rs.3.rs-153628. doi: 10.21203/rs.3.rs-153628/v1. Res Sq. 2021. Update in: Nature. 2022 Jun;606(7914):576-584. doi: 10.1038/s41586-022-04702-4 PMID: 34401873 Free PMC article. Updated. Preprint.
Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. bioRxiv [Preprint]. 2020 Nov 11:2020.11.11.378778. doi: 10.1101/2020.11.11.378778. bioRxiv. 2020. Update in: Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4 PMID: 33200136 Free PMC article. Updated. Preprint.
252 results