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p53 partial loss-of-function mutations sensitize to chemotherapy.
Klimovich B, Merle N, Neumann M, Elmshäuser S, Nist A, Mernberger M, Kazdal D, Stenzinger A, Timofeev O, Stiewe T. Klimovich B, et al. Among authors: neumann m. Oncogene. 2022 Feb;41(7):1011-1023. doi: 10.1038/s41388-021-02141-5. Epub 2021 Dec 14. Oncogene. 2022. PMID: 34907344 Free PMC article.
Partial p53 reactivation is sufficient to induce cancer regression.
Klimovich B, Meyer L, Merle N, Neumann M, König AM, Ananikidis N, Keber CU, Elmshäuser S, Timofeev O, Stiewe T. Klimovich B, et al. Among authors: neumann m. J Exp Clin Cancer Res. 2022 Mar 2;41(1):80. doi: 10.1186/s13046-022-02269-6. J Exp Clin Cancer Res. 2022. PMID: 35232479 Free PMC article.
Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase.
Merle N, Elmshäuser S, Strassheimer F, Wanzel M, König AM, Funk J, Neumann M, Kochhan K, Helmprobst F, Pagenstecher A, Nist A, Mernberger M, Schneider A, Braun T, Borggrefe T, Savai R, Timofeev O, Stiewe T. Merle N, et al. Among authors: neumann m. Mol Cancer. 2022 Oct 3;21(1):191. doi: 10.1186/s12943-022-01661-2. Mol Cancer. 2022. PMID: 36192757 Free PMC article.
Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.
Funk JS, Klimovich M, Drangenstein D, Pielhoop O, Hunold P, Borowek A, Noeparast M, Pavlakis E, Neumann M, Balourdas DI, Kochhan K, Merle N, Bullwinkel I, Wanzel M, Elmshäuser S, Teply-Szymanski J, Nist A, Procida T, Bartkuhn M, Humpert K, Mernberger M, Savai R, Soussi T, Joerger AC, Stiewe T. Funk JS, et al. Among authors: neumann m. Nat Genet. 2025 Jan;57(1):140-153. doi: 10.1038/s41588-024-02039-4. Epub 2025 Jan 7. Nat Genet. 2025. PMID: 39774325 Free PMC article.
App-Based Coaching to Prevent Addictive Behaviors in Vocational School Students: A Cluster Randomized Trial.
Guertler D, Schmidt H, Neumann M, Brandt D, Dreißigacker A, Bläsing D, Möhring A, Meyer C, Bischof A, Bischof G, Sürig S, Rehbein F, Hohls L, Borgwardt S, Wurm S, Haug S, Rumpf HJ. Guertler D, et al. Among authors: neumann m. J Adolesc Health. 2025 Jan 16:S1054-139X(24)00562-7. doi: 10.1016/j.jadohealth.2024.11.010. Online ahead of print. J Adolesc Health. 2025. PMID: 39818651 Free article.
1,768 results