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Replacement of heme by soluble guanylate cyclase (sGC) activators abolishes heme-nitric oxide/oxygen (H-NOX) domain structural plasticity.
Curr Res Struct Biol. 2021 Nov 18;3:324-336. doi: 10.1016/j.crstbi.2021.11.003. eCollection 2021.
Curr Res Struct Biol. 2021.
PMID: 34901882
Free PMC article.
Mapping of the sGC Stimulator BAY 41-2272 Binding Site on H-NOX Domain and Its Regulation by the Redox State of the Heme.
Makrynitsa GI, Argyriou AI, Zompra AA, Salagiannis K, Vazoura V, Papapetropoulos A, Topouzis S, Spyroulias GA.
Makrynitsa GI, et al. Among authors: vazoura v.
Front Cell Dev Biol. 2022 Jun 17;10:925457. doi: 10.3389/fcell.2022.925457. eCollection 2022.
Front Cell Dev Biol. 2022.
PMID: 35784456
Free PMC article.
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Design, synthesis and biological evaluation of new 3,4-dihydroquinoxalin-2(1H)-one derivatives as soluble guanylyl cyclase (sGC) activators.
Kintos DP, Salagiannis K, Vazoura V, Wittrien T, Papakyriakou A, Nikolaropoulos SS, Behrends S, Topouzis S, Fousteris MA.
Kintos DP, et al. Among authors: vazoura v.
Heliyon. 2022 Nov 6;8(11):e11438. doi: 10.1016/j.heliyon.2022.e11438. eCollection 2022 Nov.
Heliyon. 2022.
PMID: 36387474
Free PMC article.
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