Gubas A - Search Results

1

Metabolic Rewiring Is Essential for AML Cell Survival to Overcome Autophagy Inhibition by Loss of ATG3.

Baker F, Polat IH, Abou-El-Ardat K, Alshamleh I, Thoelken M, Hymon D, Gubas A, Koschade SE, Vischedyk JB, Kaulich M, Schwalbe H, Shaid S, Brandts CH. Baker F, et al. Among authors: gubas a. Cancers (Basel). 2021 Dec 6;13(23):6142. doi: 10.3390/cancers13236142. Cancers (Basel). 2021. PMID: 34885250 Free PMC article.

2

Minimized combinatorial CRISPR screens identify genetic interactions in autophagy.

Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Müller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I, Kaulich M. Diehl V, et al. Among authors: gubas a. Nucleic Acids Res. 2021 Jun 4;49(10):5684-5704. doi: 10.1093/nar/gkab309. Nucleic Acids Res. 2021. PMID: 33956155 Free PMC article.

3

Deciphering the mitophagy receptor network identifies a crucial role for OPTN (optineurin) in acute myeloid leukemia.

Meyer LM, Koschade SE, Vischedyk JB, Thoelken M, Gubas A, Wegner M, Basoglu M, Knapp S, Kaulich M, Eimer S, Shaid S, Brandts CH. Meyer LM, et al. Among authors: gubas a. Autophagy. 2023 Nov;19(11):2982-2996. doi: 10.1080/15548627.2023.2230839. Epub 2023 Jul 13. Autophagy. 2023. PMID: 37439113 Free PMC article.

4

A guide to the regulation of selective autophagy receptors.

Gubas A, Dikic I. Gubas A, et al. FEBS J. 2022 Jan;289(1):75-89. doi: 10.1111/febs.15824. Epub 2021 Apr 5. FEBS J. 2022. PMID: 33730405 Free article. Review.

5

PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.

McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Miranda de Stegmann D, Bhogaraju S, Maddi K, Kirchof A, Gatti E, Helfrich MH, Wakatsuki S, Behrends C, Pierre P, Dikic I. McEwan DG, et al. Among authors: gubas a. Mol Cell. 2015 Jan 8;57(1):39-54. doi: 10.1016/j.molcel.2014.11.006. Epub 2014 Dec 11. Mol Cell. 2015. PMID: 25498145 Free article.

6

The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways.

Gubas A, Karantanou C, Popovic D, Tascher G, Hoffmann ME, Platzek A, Dawe N, Dikic I, Krause DS, McEwan DG. Gubas A, et al. FEBS Lett. 2021 Apr;595(7):864-880. doi: 10.1002/1873-3468.14041. Epub 2021 Feb 28. FEBS Lett. 2021. PMID: 33452816 Free article.

7

ER remodeling via ER-phagy.

Gubas A, Dikic I. Gubas A, et al. Mol Cell. 2022 Apr 21;82(8):1492-1500. doi: 10.1016/j.molcel.2022.02.018. Mol Cell. 2022. PMID: 35452617 Free PMC article. Review.

8

Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation.

Lu G, Yi J, Gubas A, Wang YT, Wu Y, Ren Y, Wu M, Shi Y, Ouyang C, Tan HWS, Wang T, Wang L, Yang ND, Deng S, Xia D, Chen RH, Tooze SA, Shen HM. Lu G, et al. Among authors: gubas a. Autophagy. 2019 Nov;15(11):1917-1934. doi: 10.1080/15548627.2019.1596484. Epub 2019 Mar 30. Autophagy. 2019. PMID: 30898011 Free PMC article.

9

A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities.

Jelani M, Dooley HC, Gubas A, Mohamoud HSA, Khan MTM, Ali Z, Kang C, Rahim F, Jan A, Vadgama N, Khan MI, Al-Aama JY, Khan A, Tooze SA, Nasir J. Jelani M, et al. Among authors: gubas a. Brain. 2019 May 1;142(5):1242-1254. doi: 10.1093/brain/awz075. Brain. 2019. PMID: 30968111 Free PMC article.

10

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons.

Stavoe AK, Gopal PP, Gubas A, Tooze SA, Holzbaur EL. Stavoe AK, et al. Among authors: gubas a. Elife. 2019 Jul 16;8:e44219. doi: 10.7554/eLife.44219. Elife. 2019. PMID: 31309927 Free PMC article.

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