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22 results

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Page 1
Randomized trial of neoadjuvant vaccination with tumor-cell lysate induces T cell response in low-grade gliomas.
Ogino H, Taylor JW, Nejo T, Gibson D, Watchmaker PB, Okada K, Saijo A, Tedesco MR, Shai A, Wong CM, Rabbitt JE, Olin MR, Moertel CL, Nishioka Y, Salazar AM, Molinaro AM, Phillips JJ, Butowski NA, Clarke JL, Oberheim Bush NA, Hervey-Jumper SL, Theodosopoulos P, Chang SM, Berger MS, Okada H. Ogino H, et al. Among authors: watchmaker pb. J Clin Invest. 2022 Feb 1;132(3):e151239. doi: 10.1172/JCI151239. J Clin Invest. 2022. PMID: 34882581 Free PMC article. Clinical Trial.
Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas.
Kohanbash G, Carrera DA, Shrivastav S, Ahn BJ, Jahan N, Mazor T, Chheda ZS, Downey KM, Watchmaker PB, Beppler C, Warta R, Amankulor NA, Herold-Mende C, Costello JF, Okada H. Kohanbash G, et al. Among authors: watchmaker pb. J Clin Invest. 2017 Apr 3;127(4):1425-1437. doi: 10.1172/JCI90644. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319047 Free PMC article.
Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment.
Müller S, Kohanbash G, Liu SJ, Alvarado B, Carrera D, Bhaduri A, Watchmaker PB, Yagnik G, Di Lullo E, Malatesta M, Amankulor NM, Kriegstein AR, Lim DA, Aghi M, Okada H, Diaz A. Müller S, et al. Among authors: watchmaker pb. Genome Biol. 2017 Dec 20;18(1):234. doi: 10.1186/s13059-017-1362-4. Genome Biol. 2017. PMID: 29262845 Free PMC article.
Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H. Mueller S, et al. Among authors: watchmaker pb. J Clin Invest. 2020 Dec 1;130(12):6325-6337. doi: 10.1172/JCI140378. J Clin Invest. 2020. PMID: 32817593 Free PMC article. Clinical Trial.
Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.
Chuntova P, Chow F, Watchmaker PB, Galvez M, Heimberger AB, Newell EW, Diaz A, DePinho RA, Li MO, Wherry EJ, Mitchell D, Terabe M, Wainwright DA, Berzofsky JA, Herold-Mende C, Heath JR, Lim M, Margolin KA, Chiocca EA, Kasahara N, Ellingson BM, Brown CE, Chen Y, Fecci PE, Reardon DA, Dunn GP, Liau LM, Costello JF, Wick W, Cloughesy T, Timmer WC, Wen PY, Prins RM, Platten M, Okada H. Chuntova P, et al. Among authors: watchmaker pb. Neuro Oncol. 2021 Mar 25;23(3):356-375. doi: 10.1093/neuonc/noaa277. Neuro Oncol. 2021. PMID: 33367885 Free PMC article. Review.
Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H. Mueller S, et al. Among authors: watchmaker pb. J Clin Invest. 2022 Jun 15;132(12):e162283. doi: 10.1172/JCI162283. J Clin Invest. 2022. PMID: 35703183 Free PMC article. No abstract available.
Glioma-neuronal circuit remodeling induces regional immunosuppression.
Nejo T, Krishna S, Jimenez C, Yamamichi A, Young JS, Lakshmanachetty S, Chen T, Phyu SSS, Ogino H, Watchmaker P, Diebold D, Choudhury A, Daniel AGS, Raleigh DR, Hervey-Jumper SL, Okada H. Nejo T, et al. bioRxiv [Preprint]. 2023 Aug 6:2023.08.04.548295. doi: 10.1101/2023.08.04.548295. bioRxiv. 2023. PMID: 37577659 Free PMC article. Preprint.
A combinatory vaccine with IMA950 plus varlilumab promotes effector memory T-cell differentiation in the peripheral blood of patients with low-grade gliomas.
Saijo A, Ogino H, Butowski NA, Tedesco MR, Gibson D, Watchmaker PB, Okada K, Wang AS, Shai A, Salazar AM, Molinaro AM, Rabbitt JE, Shahin M, Perry A, Clarke JL, Taylor JW, Daras M, Oberheim Bush NA, Hervey-Jumper SL, Phillips JJ, Chang SM, Hilf N, Mayer-Mokler A, Keler T, Berger MS, Okada H. Saijo A, et al. Among authors: watchmaker pb. Neuro Oncol. 2024 Feb 2;26(2):335-347. doi: 10.1093/neuonc/noad185. Neuro Oncol. 2024. PMID: 37758193 Free PMC article. Clinical Trial.
Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens.
Kwok DW, Stevers NO, Nejo T, Chen LH, Etxeberria I, Jung J, Okada K, Cove MC, Lakshmanachetty S, Gallus M, Barpanda A, Hong C, Chan GKL, Wu SH, Ramos E, Yamamichi A, Liu J, Watchmaker P, Ogino H, Saijo A, Du A, Grishanina N, Woo J, Diaz A, Chang SM, Phillips JJ, Wiita AP, Klebanoff CA, Costello JF, Okada H. Kwok DW, et al. bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563178. doi: 10.1101/2023.10.19.563178. bioRxiv. 2023. PMID: 37904942 Free PMC article. Preprint.
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