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Page 1
Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome.
Rizzo AN, Haeger SM, Oshima K, Yang Y, Wallbank AM, Jin Y, Lettau M, McCaig LA, Wickersham NE, McNeil JB, Zakharevich I, McMurtry SA, Langouët-Astrié CJ, Kopf KW, Voelker DR, Hansen KC, Shaver CM, Kerchberger VE, Peterson RA, Kuebler WM, Ochs M, Veldhuizen RA, Smith BJ, Ware LB, Bastarache JA, Schmidt EP. Rizzo AN, et al. Among authors: mcmurtry sa. JCI Insight. 2022 Jan 25;7(2):e154573. doi: 10.1172/jci.insight.154573. JCI Insight. 2022. PMID: 34874923 Free PMC article.
Circulating heparan sulfate fragments mediate septic cognitive dysfunction.
Hippensteel JA, Anderson BJ, Orfila JE, McMurtry SA, Dietz RM, Su G, Ford JA, Oshima K, Yang Y, Zhang F, Han X, Yu Y, Liu J, Linhardt RJ, Meyer NJ, Herson PS, Schmidt EP. Hippensteel JA, et al. Among authors: mcmurtry sa. J Clin Invest. 2019 Apr 1;129(4):1779-1784. doi: 10.1172/JCI124485. Epub 2019 Mar 18. J Clin Invest. 2019. PMID: 30720464 Free PMC article.
Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions.
Zhang X, Han X, Xia K, Xu Y, Yang Y, Oshima K, Haeger SM, Perez MJ, McMurtry SA, Hippensteel JA, Ford JA, Herson PS, Liu J, Schmidt EP, Linhardt RJ. Zhang X, et al. Among authors: mcmurtry sa. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9208-9213. doi: 10.1073/pnas.1902227116. Epub 2019 Apr 22. Proc Natl Acad Sci U S A. 2019. PMID: 31010931 Free PMC article.
Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.
Oshima K, Han X, Ouyang Y, El Masri R, Yang Y, Haeger SM, McMurtry SA, Lane TC, Davizon-Castillo P, Zhang F, Yue X, Vivès RR, Linhardt RJ, Schmidt EP. Oshima K, et al. Among authors: mcmurtry sa. Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L667-L677. doi: 10.1152/ajplung.00175.2019. Epub 2019 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31461325 Free PMC article.
Alveolar heparan sulfate shedding impedes recovery from bleomycin-induced lung injury.
LaRivière WB, Liao S, McMurtry SA, Oshima K, Han X, Zhang F, Yan S, Haeger SM, Ransom M, Bastarache JA, Linhardt RJ, Schmidt EP, Yang Y. LaRivière WB, et al. Among authors: mcmurtry sa. Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1;318(6):L1198-L1210. doi: 10.1152/ajplung.00063.2020. Epub 2020 Apr 22. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32320623 Free PMC article.
The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia.
Langouët-Astrié C, Oshima K, McMurtry SA, Yang Y, Kwiecinski JM, LaRivière WB, Kavanaugh JS, Zakharevich I, Hansen KC, Shi D, Zhang F, Boguslawski KM, Perelman SS, Su G, Torres VJ, Liu J, Horswill AR, Schmidt EP. Langouët-Astrié C, et al. Among authors: mcmurtry sa. Cell Rep. 2022 Nov 29;41(9):111721. doi: 10.1016/j.celrep.2022.111721. Cell Rep. 2022. PMID: 36450248 Free PMC article.
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