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Page 1
VEGFA mRNA for regenerative treatment of heart failure.
Collén A, Bergenhem N, Carlsson L, Chien KR, Hoge S, Gan LM, Fritsche-Danielson R. Collén A, et al. Among authors: chien kr. Nat Rev Drug Discov. 2022 Jan;21(1):79-80. doi: 10.1038/s41573-021-00355-6. Nat Rev Drug Discov. 2022. PMID: 34873303 Free PMC article. No abstract available.
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.
Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR. Zangi L, et al. Among authors: chien kr. Nat Biotechnol. 2013 Oct;31(10):898-907. doi: 10.1038/nbt.2682. Epub 2013 Sep 8. Nat Biotechnol. 2013. PMID: 24013197 Free PMC article.
Biocompatible, Purified VEGF-A mRNA Improves Cardiac Function after Intracardiac Injection 1 Week Post-myocardial Infarction in Swine.
Carlsson L, Clarke JC, Yen C, Gregoire F, Albery T, Billger M, Egnell AC, Gan LM, Jennbacken K, Johansson E, Linhardt G, Martinsson S, Sadiq MW, Witman N, Wang QD, Chen CH, Wang YP, Lin S, Ticho B, Hsieh PCH, Chien KR, Fritsche-Danielson R. Carlsson L, et al. Among authors: chien kr. Mol Ther Methods Clin Dev. 2018 Apr 10;9:330-346. doi: 10.1016/j.omtm.2018.04.003. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2018. PMID: 30038937 Free PMC article.
Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing.
Sun N, Ning B, Hansson KM, Bruce AC, Seaman SA, Zhang C, Rikard M, DeRosa CA, Fraser CL, Wågberg M, Fritsche-Danielson R, Wikström J, Chien KR, Lundahl A, Hölttä M, Carlsson LG, Peirce SM, Hu S. Sun N, et al. Among authors: chien kr. Sci Rep. 2018 Nov 30;8(1):17509. doi: 10.1038/s41598-018-35570-6. Sci Rep. 2018. PMID: 30504800 Free PMC article.
Regenerating the field of cardiovascular cell therapy.
Chien KR, Frisén J, Fritsche-Danielson R, Melton DA, Murry CE, Weissman IL. Chien KR, et al. Nat Biotechnol. 2019 Mar;37(3):232-237. doi: 10.1038/s41587-019-0042-1. Epub 2019 Feb 18. Nat Biotechnol. 2019. PMID: 30778231 Review.
Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes.
Gan LM, Lagerström-Fermér M, Carlsson LG, Arfvidsson C, Egnell AC, Rudvik A, Kjaer M, Collén A, Thompson JD, Joyal J, Chialda L, Koernicke T, Fuhr R, Chien KR, Fritsche-Danielson R. Gan LM, et al. Among authors: chien kr. Nat Commun. 2019 Feb 20;10(1):871. doi: 10.1038/s41467-019-08852-4. Nat Commun. 2019. PMID: 30787295 Free PMC article.
Model-Based Analysis Reveals a Sustained and Dose-Dependent Acceleration of Wound Healing by VEGF-A mRNA (AZD8601).
Almquist J, Rikard SM, Wågberg M, Bruce AC, Gennemark P, Fritsche-Danielson R, Chien KR, Peirce SM, Hansson K, Lundahl A. Almquist J, et al. Among authors: chien kr. CPT Pharmacometrics Syst Pharmacol. 2020 Jul;9(7):384-394. doi: 10.1002/psp4.12516. Epub 2020 Jul 5. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32438492 Free PMC article.
349 results