Yang KW - Search Results

1

Hydroxamates as a potent skeleton for the development of metallo-β-lactamase inhibitors.

Chigan JZ, Li JQ, Ding HH, Xu YS, Liu L, Chen C, Yang KW. Chigan JZ, et al. Among authors: yang kw. Chem Biol Drug Des. 2022 Feb;99(2):362-372. doi: 10.1111/cbdd.13990. Epub 2021 Dec 10. Chem Biol Drug Des. 2022. PMID: 34862744

2

N-heterocyclic dicarboxylic acids: broad-spectrum inhibitors of metallo-β-lactamases with co-antibacterial effect against antibiotic-resistant bacteria.

Feng L, Yang KW, Zhou LS, Xiao JM, Yang X, Zhai L, Zhang YL, Crowder MW. Feng L, et al. Among authors: yang x, yang kw. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5185-9. doi: 10.1016/j.bmcl.2012.06.074. Epub 2012 Jul 1. Bioorg Med Chem Lett. 2012. PMID: 22796180

3

New β-phospholactam as a carbapenem transition state analog: Synthesis of a broad-spectrum inhibitor of metallo-β-lactamases.

Yang KW, Feng L, Yang SK, Aitha M, LaCuran AE, Oelschlaeger P, Crowder MW. Yang KW, et al. Among authors: yang sk. Bioorg Med Chem Lett. 2013 Nov 1;23(21):5855-9. doi: 10.1016/j.bmcl.2013.08.098. Epub 2013 Sep 8. Bioorg Med Chem Lett. 2013. PMID: 24064498 Free PMC article.

4

Diaryl-substituted azolylthioacetamides: Inhibitor discovery of New Delhi metallo-β-lactamase-1 (NDM-1).

Zhang YL, Yang KW, Zhou YJ, LaCuran AE, Oelschlaeger P, Crowder MW. Zhang YL, et al. Among authors: yang kw. ChemMedChem. 2014 Nov;9(11):2445-8. doi: 10.1002/cmdc.201402249. Epub 2014 Jul 22. ChemMedChem. 2014. PMID: 25048031

5

Azolylthioacetamide: A Highly Promising Scaffold for the Development of Metallo-β-lactamase Inhibitors.

Yang SK, Kang JS, Oelschlaeger P, Yang KW. Yang SK, et al. Among authors: yang kw. ACS Med Chem Lett. 2015 Feb 12;6(4):455-60. doi: 10.1021/ml500534c. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25893049 Free PMC article.

6

Amino Acid Thioester Derivatives: A Highly Promising Scaffold for the Development of Metallo-β-lactamase L1 Inhibitors.

Liu XL, Shi Y, Kang JS, Oelschlaeger P, Yang KW. Liu XL, et al. Among authors: yang kw. ACS Med Chem Lett. 2015 Apr 23;6(6):660-4. doi: 10.1021/acsmedchemlett.5b00098. eCollection 2015 Jun 11. ACS Med Chem Lett. 2015. PMID: 26101570 Free PMC article.

7

Optimization of amino acid thioesters as inhibitors of metallo-β-lactamase L1.

Liu XL, Yang KW, Zhang YJ, Ge Y, Xiang Y, Chang YN, Oelschlaeger P. Liu XL, et al. Among authors: yang kw. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4698-4701. doi: 10.1016/j.bmcl.2016.08.048. Epub 2016 Aug 22. Bioorg Med Chem Lett. 2016. PMID: 27595424

8

The structure of the metallo-β-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor.

Christopeit T, Yang KW, Yang SK, Leiros HK. Christopeit T, et al. Among authors: yang sk, yang kw. Acta Crystallogr F Struct Biol Commun. 2016 Nov 1;72(Pt 11):813-819. doi: 10.1107/S2053230X16016113. Epub 2016 Oct 24. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27834790 Free PMC article.

9

Characterization of β-lactamase activity using isothermal titration calorimetry.

Wang WJ, Wang Q, Zhang Y, Lu R, Zhang YL, Yang KW, Lei JE, He Y. Wang WJ, et al. Among authors: yang kw. Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):2031-2038. doi: 10.1016/j.bbagen.2017.04.011. Epub 2017 Apr 25. Biochim Biophys Acta Gen Subj. 2017. PMID: 28454737

10

Carbamylmethyl Mercaptoacetate Thioether: A Novel Scaffold for the Development of L1 Metallo-β-lactamase Inhibitors.

Chang YN, Xiang Y, Zhang YJ, Wang WM, Chen C, Oelschlaeger P, Yang KW. Chang YN, et al. Among authors: yang kw. ACS Med Chem Lett. 2017 Apr 24;8(5):527-532. doi: 10.1021/acsmedchemlett.7b00058. eCollection 2017 May 11. ACS Med Chem Lett. 2017. PMID: 28523105 Free PMC article.

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