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Structural Basis of CD160:HVEM Recognition.
Liu W, Garrett SC, Fedorov EV, Ramagopal UA, Garforth SJ, Bonanno JB, Almo SC. Liu W, et al. Among authors: garforth sj. Structure. 2019 Aug 6;27(8):1286-1295.e4. doi: 10.1016/j.str.2019.05.010. Epub 2019 Jun 20. Structure. 2019. PMID: 31230945 Free PMC article.
HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
Liu W, Chou TF, Garrett-Thomson SC, Seo GY, Fedorov E, Ramagopal UA, Bonanno JB, Wang Q, Kim K, Garforth SJ, Kakugawa K, Cheroutre H, Kronenberg M, Almo SC. Liu W, et al. Among authors: garforth sj. J Exp Med. 2021 Dec 6;218(12):e20211112. doi: 10.1084/jem.20211112. Epub 2021 Oct 28. J Exp Med. 2021. PMID: 34709351 Free PMC article.
Anti-CTLA-4 therapy requires an Fc domain for efficacy.
Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M. Ingram JR, et al. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3912-3917. doi: 10.1073/pnas.1801524115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581255 Free PMC article.
Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex.
Garrett-Thomson SC, Massimi A, Fedorov EV, Bonanno JB, Scandiuzzi L, Hillerich B, Seidel RD 3rd, Love JD, Garforth SJ, Guha C, Almo SC. Garrett-Thomson SC, et al. Among authors: garforth sj. PLoS One. 2020 Jun 4;15(6):e0233578. doi: 10.1371/journal.pone.0233578. eCollection 2020. PLoS One. 2020. PMID: 32497097 Free PMC article.
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