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Structure guided studies of the interaction between PTP1B and JAK.
Morris R, Keating N, Tan C, Chen H, Laktyushin A, Saiyed T, Liau NPD, Nicola NA, Tiganis T, Kershaw NJ, Babon JJ. Morris R, et al. Among authors: tan c. Commun Biol. 2023 Jun 14;6(1):641. doi: 10.1038/s42003-023-05020-9. Commun Biol. 2023. PMID: 37316570 Free PMC article.
Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.
Linossi EM, Li K, Veggiani G, Tan C, Dehkhoda F, Hockings C, Calleja DJ, Keating N, Feltham R, Brooks AJ, Li SS, Sidhu SS, Babon JJ, Kershaw NJ, Nicholson SE. Linossi EM, et al. Among authors: tan c. Nat Commun. 2023 Dec 1;14(1):7951. doi: 10.1038/s41467-023-42706-4. Nat Commun. 2023. PMID: 38040684 Free PMC article. No abstract available.
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity.
Gilson PR, Tan C, Jarman KE, Lowes KN, Curtis JM, Nguyen W, Di Rago AE, Bullen HE, Prinz B, Duffy S, Baell JB, Hutton CA, Jousset Subroux H, Crabb BS, Avery VM, Cowman AF, Sleebs BE. Gilson PR, et al. Among authors: tan c. J Med Chem. 2017 Feb 9;60(3):1171-1188. doi: 10.1021/acs.jmedchem.6b01673. Epub 2017 Jan 26. J Med Chem. 2017. PMID: 28080063
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