Sidhu SS - Search Results

1

Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.

Linossi EM, Li K, Veggiani G, Tan C, Dehkhoda F, Hockings C, Calleja DJ, Keating N, Feltham R, Brooks AJ, Li SS, Sidhu SS, Babon JJ, Kershaw NJ, Nicholson SE. Linossi EM, et al. Among authors: sidhu ss. Nat Commun. 2021 Dec 2;12(1):7032. doi: 10.1038/s41467-021-26983-5. Nat Commun. 2021. PMID: 34857742 Free PMC article.

2

Evolving specificity from variability for protein interaction domains.

Kaneko T, Sidhu SS, Li SS. Kaneko T, et al. Among authors: sidhu ss. Trends Biochem Sci. 2011 Apr;36(4):183-90. doi: 10.1016/j.tibs.2010.12.001. Epub 2011 Jan 10. Trends Biochem Sci. 2011. PMID: 21227701

3

Superbinder SH2 domains act as antagonists of cell signaling.

Kaneko T, Huang H, Cao X, Li X, Li C, Voss C, Sidhu SS, Li SS. Kaneko T, et al. Among authors: sidhu ss. Sci Signal. 2012 Sep 25;5(243):ra68. doi: 10.1126/scisignal.2003021. Sci Signal. 2012. PMID: 23012655

4

Protein-phosphotyrosine proteome profiling by superbinder-SH2 domain affinity purification mass spectrometry, sSH2-AP-MS.

Tong J, Cao B, Martyn GD, Krieger JR, Taylor P, Yates B, Sidhu SS, Li SS, Mao X, Moran MF. Tong J, et al. Among authors: sidhu ss. Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600360. Epub 2017 Jan 17. Proteomics. 2017. PMID: 27880036

5

Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain.

Huang H, Kaneko T, Sidhu SS, Li SS. Huang H, et al. Among authors: sidhu ss. Methods Mol Biol. 2017;1555:225-254. doi: 10.1007/978-1-4939-6762-9_13. Methods Mol Biol. 2017. PMID: 28092036

6

Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif.

Manczyk N, Yates BP, Veggiani G, Ernst A, Sicheri F, Sidhu SS. Manczyk N, et al. Among authors: sidhu ss. Protein Sci. 2017 May;26(5):1060-1069. doi: 10.1002/pro.3155. Epub 2017 Mar 24. Protein Sci. 2017. PMID: 28276594 Free PMC article.

7

Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis.

Veggiani G, Huang H, Yates BP, Tong J, Kaneko T, Joshi R, Li SSC, Moran MF, Gish G, Sidhu SS. Veggiani G, et al. Among authors: sidhu ss. Protein Sci. 2019 Feb;28(2):403-413. doi: 10.1002/pro.3551. Epub 2018 Dec 24. Protein Sci. 2019. PMID: 30431205 Free PMC article.

8

Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif.

Manczyk N, Veggiani G, Gish GD, Yates BP, Ernst A, Sidhu SS, Sicheri F. Manczyk N, et al. Among authors: sidhu ss. Protein Sci. 2019 May;28(5):848-856. doi: 10.1002/pro.3593. Epub 2019 Mar 12. Protein Sci. 2019. PMID: 30793400 Free PMC article.

9

Emerging drug development technologies targeting ubiquitination for cancer therapeutics.

Veggiani G, Gerpe MCR, Sidhu SS, Zhang W. Veggiani G, et al. Among authors: sidhu ss. Pharmacol Ther. 2019 Jul;199:139-154. doi: 10.1016/j.pharmthera.2019.03.003. Epub 2019 Mar 7. Pharmacol Ther. 2019. PMID: 30851297 Free PMC article. Review.

10

The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency.

Manczyk N, Veggiani G, Teyra J, Strilchuk AW, Sidhu SS, Sicheri F. Manczyk N, et al. Among authors: sidhu ss. Sci Rep. 2019 Mar 11;9(1):4119. doi: 10.1038/s41598-019-40815-z. Sci Rep. 2019. PMID: 30858488 Free PMC article.

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