Babon JJ - Search Results

1

Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.

Linossi EM, Li K, Veggiani G, Tan C, Dehkhoda F, Hockings C, Calleja DJ, Keating N, Feltham R, Brooks AJ, Li SS, Sidhu SS, Babon JJ, Kershaw NJ, Nicholson SE. Linossi EM, et al. Among authors: babon jj. Nat Commun. 2021 Dec 2;12(1):7032. doi: 10.1038/s41467-021-26983-5. Nat Commun. 2021. PMID: 34857742 Free PMC article.

2

Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2).

Yao S, Masters SL, Zhang JG, Palmer KR, Babon JJ, Nicola NA, Nicholson SE, Norton RS. Yao S, et al. Among authors: babon jj. J Biomol NMR. 2005 Jan;31(1):69-70. doi: 10.1007/s10858-004-6924-6. J Biomol NMR. 2005. PMID: 15692743 No abstract available.

3

Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain.

Babon JJ, Yao S, DeSouza DP, Harrison CF, Fabri LJ, Liepinsh E, Scrofani SD, Baca M, Norton RS. Babon JJ, et al. FEBS J. 2005 Dec;272(23):6120-30. doi: 10.1111/j.1742-4658.2005.05010.x. FEBS J. 2005. PMID: 16302975 Free article.

4

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.

Masters SL, Yao S, Willson TA, Zhang JG, Palmer KR, Smith BJ, Babon JJ, Nicola NA, Norton RS, Nicholson SE. Masters SL, et al. Among authors: babon jj. Nat Struct Mol Biol. 2006 Jan;13(1):77-84. doi: 10.1038/nsmb1034. Epub 2005 Dec 20. Nat Struct Mol Biol. 2006. PMID: 16369487

5

The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

Babon JJ, McManus EJ, Yao S, DeSouza DP, Mielke LA, Sprigg NS, Willson TA, Hilton DJ, Nicola NA, Baca M, Nicholson SE, Norton RS. Babon JJ, et al. Mol Cell. 2006 Apr 21;22(2):205-16. doi: 10.1016/j.molcel.2006.03.024. Mol Cell. 2006. PMID: 16630890 Free article.

6

Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops.

Yao S, Liu MS, Masters SL, Zhang JG, Babon JJ, Nicola NA, Nicholson SE, Norton RS. Yao S, et al. Among authors: babon jj. Protein Sci. 2006 Dec;15(12):2761-72. doi: 10.1110/ps.062477806. Epub 2006 Nov 6. Protein Sci. 2006. PMID: 17088318 Free PMC article.

7

Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation.

Boyle K, Zhang JG, Nicholson SE, Trounson E, Babon JJ, McManus EJ, Nicola NA, Robb L. Boyle K, et al. Among authors: babon jj. Cell Signal. 2009 Mar;21(3):394-404. doi: 10.1016/j.cellsig.2008.11.002. Epub 2008 Nov 12. Cell Signal. 2009. PMID: 19056487 Free PMC article.

8

The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.

Kuang Z, Lewis RS, Curtis JM, Zhan Y, Saunders BM, Babon JJ, Kolesnik TB, Low A, Masters SL, Willson TA, Kedzierski L, Yao S, Handman E, Norton RS, Nicholson SE. Kuang Z, et al. Among authors: babon jj. J Cell Biol. 2010 Jul 12;190(1):129-41. doi: 10.1083/jcb.200912087. Epub 2010 Jul 5. J Cell Biol. 2010. PMID: 20603330 Free PMC article.

9

Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity.

Babon JJ, Kershaw NJ, Murphy JM, Varghese LN, Laktyushin A, Young SN, Lucet IS, Norton RS, Nicola NA. Babon JJ, et al. Immunity. 2012 Feb 24;36(2):239-50. doi: 10.1016/j.immuni.2011.12.015. Immunity. 2012. PMID: 22342841 Free PMC article.

10

The biology and mechanism of action of suppressor of cytokine signaling 3.

Babon JJ, Nicola NA. Babon JJ, et al. Growth Factors. 2012 Aug;30(4):207-19. doi: 10.3109/08977194.2012.687375. Epub 2012 May 11. Growth Factors. 2012. PMID: 22574771 Free PMC article. Review.

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