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Page 1
Fluorinated rhamnosides inhibit cellular fucosylation.
Pijnenborg JFA, Rossing E, Merx J, Noga MJ, Titulaer WHC, Eerden N, Veizaj R, White PB, Lefeber DJ, Boltje TJ. Pijnenborg JFA, et al. Among authors: lefeber dj. Nat Commun. 2021 Dec 2;12(1):7024. doi: 10.1038/s41467-021-27355-9. Nat Commun. 2021. PMID: 34857733 Free PMC article.
Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands.
Büll C, Heise T, Beurskens DM, Riemersma M, Ashikov A, Rutjes FP, van Kuppevelt TH, Lefeber DJ, den Brok MH, Adema GJ, Boltje TJ. Büll C, et al. Among authors: lefeber dj. ACS Chem Biol. 2015 Oct 16;10(10):2353-63. doi: 10.1021/acschembio.5b00501. Epub 2015 Aug 10. ACS Chem Biol. 2015. PMID: 26258433
NANS-mediated synthesis of sialic acid is required for brain and skeletal development.
van Karnebeek CD, Bonafé L, Wen XY, Tarailo-Graovac M, Balzano S, Royer-Bertrand B, Ashikov A, Garavelli L, Mammi I, Turolla L, Breen C, Donnai D, Cormier-Daire V, Heron D, Nishimura G, Uchikawa S, Campos-Xavier B, Rossi A, Hennet T, Brand-Arzamendi K, Rozmus J, Harshman K, Stevenson BJ, Girardi E, Superti-Furga G, Dewan T, Collingridge A, Halparin J, Ross CJ, Van Allen MI, Rossi A, Engelke UF, Kluijtmans LA, van der Heeft E, Renkema H, de Brouwer A, Huijben K, Zijlstra F, Heise T, Boltje T, Wasserman WW, Rivolta C, Unger S, Lefeber DJ, Wevers RA, Superti-Furga A. van Karnebeek CD, et al. Among authors: lefeber dj. Nat Genet. 2016 Jul;48(7):777-84. doi: 10.1038/ng.3578. Epub 2016 May 23. Nat Genet. 2016. PMID: 27213289 Free article.
Combined sialic acid and histone deacetylase (HDAC) inhibitor treatment up-regulates the neuroblastoma antigen GD2.
van den Bijgaart RJE, Kroesen M, Wassink M, Brok IC, Kers-Rebel ED, Boon L, Heise T, van Scherpenzeel M, Lefeber DJ, Boltje TJ, den Brok MH, Hoogerbrugge PM, Büll C, Adema GJ. van den Bijgaart RJE, et al. Among authors: lefeber dj. J Biol Chem. 2019 Mar 22;294(12):4437-4449. doi: 10.1074/jbc.RA118.002763. Epub 2019 Jan 22. J Biol Chem. 2019. PMID: 30670592 Free PMC article.
Cellular Fucosylation Inhibitors Based on Fluorinated Fucose-1-phosphates*.
Pijnenborg JFA, Visser EA, Noga M, Rossing E, Veizaj R, Lefeber DJ, Büll C, Boltje TJ. Pijnenborg JFA, et al. Among authors: lefeber dj. Chemistry. 2021 Feb 24;27(12):4022-4027. doi: 10.1002/chem.202005359. Epub 2021 Feb 2. Chemistry. 2021. PMID: 33336886 Free PMC article.
Congenital disorder of glycosylation caused by starting site-specific variant in syntaxin-5.
Linders PTA, Gerretsen ECF, Ashikov A, Vals MA, de Boer R, Revelo NH, Arts R, Baerenfaenger M, Zijlstra F, Huijben K, Raymond K, Muru K, Fjodorova O, Pajusalu S, Õunap K, Ter Beest M, Lefeber D, van den Bogaart G. Linders PTA, et al. Nat Commun. 2021 Oct 28;12(1):6227. doi: 10.1038/s41467-021-26534-y. Nat Commun. 2021. PMID: 34711829 Free PMC article.
Dynamic tracing of sugar metabolism reveals the mechanisms of action of synthetic sugar analogs.
van Scherpenzeel M, Conte F, Büll C, Ashikov A, Hermans E, Willems A, van Tol W, Kragt E, Noga M, Moret EE, Heise T, Langereis JD, Rossing E, Zimmermann M, Rubio-Gozalbo ME, de Jonge MI, Adema GJ, Zamboni N, Boltje T, Lefeber DJ. van Scherpenzeel M, et al. Among authors: lefeber dj. Glycobiology. 2022 Mar 30;32(3):239-250. doi: 10.1093/glycob/cwab106. Glycobiology. 2022. PMID: 34939087 Free PMC article.
273 results