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Identification and characterization of an atypical Gαs-biased β2AR agonist that fails to evoke airway smooth muscle cell tachyphylaxis.
Kim D, Tokmakova A, Lujan LK, Strzelinski HR, Kim N, Najari Beidokhti M, Giulianotti MA, Mafi A, Woo JA, An SS, Goddard WA 3rd, Liggett SB. Kim D, et al. Among authors: mafi a. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2026668118. doi: 10.1073/pnas.2026668118. Proc Natl Acad Sci U S A. 2021. PMID: 34857633 Free PMC article.
Hedgehog proteins create a dynamic cholesterol interface.
Mafi A, Purohit R, Vielmas E, Lauinger AR, Lam B, Cheng YS, Zhang T, Huang Y, Kim SK, Goddard WA 3rd, Ondrus AE. Mafi A, et al. PLoS One. 2021 Feb 25;16(2):e0246814. doi: 10.1371/journal.pone.0246814. eCollection 2021. PLoS One. 2021. PMID: 33630857 Free PMC article.
Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E, protects human neurons against oxidative/neuroexcitotoxic stress via β-arrestin/ERK signaling.
Sharma VK, Yang X, Kim SK, Mafi A, Saiz-Sanchez D, Villanueva-Anguita P, Xiao L, Inoue A, Goddard WA 3rd, Loh YP. Sharma VK, et al. Among authors: mafi a. Cell Mol Life Sci. 2021 Dec 29;79(1):24. doi: 10.1007/s00018-021-04021-3. Cell Mol Life Sci. 2021. PMID: 34966948 Free PMC article.
202 results