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Identification and characterization of an atypical Gαs-biased β2AR agonist that fails to evoke airway smooth muscle cell tachyphylaxis.
Kim D, Tokmakova A, Lujan LK, Strzelinski HR, Kim N, Najari Beidokhti M, Giulianotti MA, Mafi A, Woo JA, An SS, Goddard WA 3rd, Liggett SB. Kim D, et al. Among authors: kim n. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2026668118. doi: 10.1073/pnas.2026668118. Proc Natl Acad Sci U S A. 2021. PMID: 34857633 Free PMC article.
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, Liggett SB, Panettieri RA Jr, Dong X, An SS. Huang J, et al. Among authors: kim d, kim n. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28485-28495. doi: 10.1073/pnas.2003111117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097666 Free PMC article.
Basic Science and Pathogenesis.
Cho MH, Kim MS, Han SH, Mun YS, Song HL, Kim NY, Shin JS, Kim DH, Yoon SY. Cho MH, et al. Among authors: kim ny. Alzheimers Dement. 2024 Dec;20 Suppl 1:e088124. doi: 10.1002/alz.088124. Alzheimers Dement. 2024. PMID: 39751079
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