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Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug.
Alors-Perez E, Blázquez-Encinas R, Alcalá S, Viyuela-García C, Pedraza-Arevalo S, Herrero-Aguayo V, Jiménez-Vacas JM, Mafficini A, Sánchez-Frías ME, Cano MT, Abollo-Jiménez F, Marín-Sanz JA, Cabezas-Sainz P, Lawlor RT, Luchini C, Sánchez L, Sánchez-Hidalgo JM, Ventura S, Martin-Hijano L, Gahete MD, Scarpa A, Arjona-Sánchez Á, Ibáñez-Costa A, Sainz B Jr, Luque RM, Castaño JP. Alors-Perez E, et al. Among authors: lawlor rt. J Exp Clin Cancer Res. 2021 Dec 2;40(1):382. doi: 10.1186/s13046-021-02153-9. J Exp Clin Cancer Res. 2021. PMID: 34857016 Free PMC article.
Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.
Amato E, Molin MD, Mafficini A, Yu J, Malleo G, Rusev B, Fassan M, Antonello D, Sadakari Y, Castelli P, Zamboni G, Maitra A, Salvia R, Hruban RH, Bassi C, Capelli P, Lawlor RT, Goggins M, Scarpa A. Amato E, et al. Among authors: lawlor rt. J Pathol. 2014 Jul;233(3):217-27. doi: 10.1002/path.4344. J Pathol. 2014. PMID: 24604757 Free PMC article.
Evaluation of cell-free DNA as a biomarker for pancreatic malignancies.
Sikora K, Bedin C, Vicentini C, Malpeli G, D'Angelo E, Sperandio N, Lawlor RT, Bassi C, Tortora G, Nitti D, Agostini M, Fassan M, Scarpa A. Sikora K, et al. Among authors: lawlor rt. Int J Biol Markers. 2015 Feb 24;30(1):e136-41. doi: 10.5301/jbm.5000088. Int J Biol Markers. 2015. PMID: 24832178 Free article.
Multigene mutational profiling of cholangiocarcinomas identifies actionable molecular subgroups.
Simbolo M, Fassan M, Ruzzenente A, Mafficini A, Wood LD, Corbo V, Melisi D, Malleo G, Vicentini C, Malpeli G, Antonello D, Sperandio N, Capelli P, Tomezzoli A, Iacono C, Lawlor RT, Bassi C, Hruban RH, Guglielmi A, Tortora G, de Braud F, Scarpa A. Simbolo M, et al. Among authors: lawlor rt. Oncotarget. 2014 May 15;5(9):2839-52. doi: 10.18632/oncotarget.1943. Oncotarget. 2014. PMID: 24867389 Free PMC article.
Reporting tumor molecular heterogeneity in histopathological diagnosis.
Mafficini A, Amato E, Fassan M, Simbolo M, Antonello D, Vicentini C, Scardoni M, Bersani S, Gottardi M, Rusev B, Malpeli G, Corbo V, Barbi S, Sikora KO, Lawlor RT, Tortora G, Scarpa A. Mafficini A, et al. Among authors: lawlor rt. PLoS One. 2014 Aug 15;9(8):e104979. doi: 10.1371/journal.pone.0104979. eCollection 2014. PLoS One. 2014. PMID: 25127237 Free PMC article.
A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics.
Sadanandam A, Wullschleger S, Lyssiotis CA, Grötzinger C, Barbi S, Bersani S, Körner J, Wafy I, Mafficini A, Lawlor RT, Simbolo M, Asara JM, Bläker H, Cantley LC, Wiedenmann B, Scarpa A, Hanahan D. Sadanandam A, et al. Among authors: lawlor rt. Cancer Discov. 2015 Dec;5(12):1296-313. doi: 10.1158/2159-8290.CD-15-0068. Epub 2015 Oct 7. Cancer Discov. 2015. PMID: 26446169 Free PMC article.
219 results