Kaushik D - Search Results

1

In vitro metabolism, pharmacokinetics and drug interaction potentials of emvododstat, a DHODH inhibitor.

Ma J, Kaushik D, Yeh S, Northcutt V, Babiak J, Risher N, Weetall M, Moon YC, Welch EM, Molony L, O'Keefe K, Kong R. Ma J, et al. Among authors: kaushik d. Xenobiotica. 2022 Feb;52(2):152-164. doi: 10.1080/00498254.2021.2010287. Epub 2022 Mar 25. Xenobiotica. 2022. PMID: 34846990 Free article.

2

Ataluren Pharmacokinetics in Healthy Japanese and Caucasian Subjects.

Kong R, Laskin OL, Kaushik D, Jin F, Ma J, McIntosh J, Souza M, Almstead N. Kong R, et al. Among authors: kaushik d. Clin Pharmacol Drug Dev. 2019 Feb;8(2):172-178. doi: 10.1002/cpdd.645. Epub 2019 Jan 10. Clin Pharmacol Drug Dev. 2019. PMID: 30629861 Free PMC article. Clinical Trial.

3

LC-MS/MS quantification of ataluren and ataluren acyl glucuronide in human plasma/urine: application in clinical studies.

Kaushik D, Ma J, Gu G, Hwang S, Moon YC, Kong R. Kaushik D, et al. Bioanalysis. 2020 Nov;12(21):1545-1555. doi: 10.4155/bio-2020-0214. Epub 2020 Oct 16. Bioanalysis. 2020. PMID: 33064028

4

Metabolite V, an epoxide species is a minor circulating metabolite in humans following a single oral dose of deflazacort.

Kong R, Ma J, Beers B, Kaushik D, Lin E, Goodwin E, Colacino J, Bibbiani F. Kong R, et al. Among authors: kaushik d. Pharmacol Res Perspect. 2020 Dec;8(6):e00677. doi: 10.1002/prp2.677. Pharmacol Res Perspect. 2020. PMID: 33090712 Free PMC article.

5

Pharmacokinetics and Safety of PTC596, a Novel Tubulin-Binding Agent, in Subjects With Advanced Solid Tumors.

Shapiro GI, O'Mara E, Laskin OL, Gao L, Baird JD, Spiegel RJ, Kaushik D, Weetall M, Colacino J, O'Keefe K, Branstrom A, Goodwin E, Infante J, Bedard PL, Kong R. Shapiro GI, et al. Among authors: kaushik d. Clin Pharmacol Drug Dev. 2021 Aug;10(8):940-949. doi: 10.1002/cpdd.904. Epub 2021 Jan 13. Clin Pharmacol Drug Dev. 2021. PMID: 33440067 Clinical Trial.

6

First-in-Human Studies of Pharmacokinetics and Safety of Utreloxastat (PTC857), a Novel 15-Lipooxygenase Inhibitor for the Treatment of Amyotrophic Lateral Sclerosis.

Gao L, Giannousis P, Thoolen M, Kaushik D, Latham J, Tansy A, Ma J, Johnston M, Dali M, Golden L, Klein M, Kong R, Trimmer J. Gao L, et al. Among authors: kaushik d. Clin Pharmacol Drug Dev. 2023 Feb;12(2):141-151. doi: 10.1002/cpdd.1203. Epub 2022 Dec 14. Clin Pharmacol Drug Dev. 2023. PMID: 36516010 Free PMC article. Clinical Trial.

7

A pharmacokinetic drug-drug interaction study between rosuvastatin and emvododstat, a potent anti-SARS-CoV-2 (COVID-19) DHODH (dihydroorotate dehydrogenase) inhibitor.

Morton TL, Laskin OL, Kaushik D, Lee L, Ma J, Kristensen A, O'Keefe K, Golden L, Klein M, Kong R. Morton TL, et al. Among authors: kaushik d. Pharmacol Res Perspect. 2023 Apr;11(2):e01076. doi: 10.1002/prp2.1076. Pharmacol Res Perspect. 2023. PMID: 36938928 Free PMC article.

8

LC-MS/MS methods for direct measurement of sepiapterin and tetrahydrobiopterin in human plasma and clinical applications.

Kaushik D, Gao L, Yuan K, Tang B, Kong R. Kaushik D, et al. Bioanalysis. 2024 Jan;16(2):75-89. doi: 10.4155/bio-2023-0144. Epub 2023 Dec 15. Bioanalysis. 2024. PMID: 38099558

9

A Phase 1 Study to Assess the Pharmacokinetics, Food Effect, Safety, and Tolerability of Sepiapterin in Healthy Japanese and Non-Japanese Participants.

Gao L, Kaushik D, Ingalls K, Smith N, Kong R. Gao L, et al. Among authors: kaushik d. Pharmaceuticals (Basel). 2024 Oct 22;17(11):1411. doi: 10.3390/ph17111411. Pharmaceuticals (Basel). 2024. PMID: 39598323 Free PMC article.

10

Comparison of quercetin pharmacokinetics following oral supplementation in humans.

Kaushik D, O'Fallon K, Clarkson PM, Dunne CP, Conca KR, Michniak-Kohn B. Kaushik D, et al. J Food Sci. 2012 Nov;77(11):H231-8. doi: 10.1111/j.1750-3841.2012.02934.x. Epub 2012 Oct 24. J Food Sci. 2012. PMID: 23094941 Clinical Trial.

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