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KLF4K409Q-mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment.
von Spreckelsen N, Waldt N, Poetschke R, Kesseler C, Dohmen H, Jiao HK, Nemeth A, Schob S, Scherlach C, Sandalcioglu IE, Deckert M, Angenstein F, Krischek B, Stavrinou P, Timmer M, Remke M, Kirches E, Goldbrunner R, Chiocca EA, Huettelmaier S, Acker T, Mawrin C. von Spreckelsen N, et al. Among authors: kirches e. Acta Neuropathol Commun. 2020 Apr 3;8(1):41. doi: 10.1186/s40478-020-00912-x. Acta Neuropathol Commun. 2020. PMID: 32245394 Free PMC article.
Crispr/Cas-based modeling of NF2 loss in meningioma cells.
Waldt N, Kesseler C, Fala P, John P, Kirches E, Angenstein F, Mawrin C. Waldt N, et al. Among authors: kirches e. J Neurosci Methods. 2021 May 15;356:109141. doi: 10.1016/j.jneumeth.2021.109141. Epub 2021 Mar 19. J Neurosci Methods. 2021. PMID: 33753124
mTORC1 inhibitors suppress meningioma growth in mouse models.
Pachow D, Andrae N, Kliese N, Angenstein F, Stork O, Wilisch-Neumann A, Kirches E, Mawrin C. Pachow D, et al. Among authors: kirches e. Clin Cancer Res. 2013 Mar 1;19(5):1180-9. doi: 10.1158/1078-0432.CCR-12-1904. Epub 2013 Feb 13. Clin Cancer Res. 2013. PMID: 23406776
The integrin inhibitor cilengitide affects meningioma cell motility and invasion.
Wilisch-Neumann A, Kliese N, Pachow D, Schneider T, Warnke JP, Braunsdorf WE, Böhmer FD, Hass P, Pasemann D, Helbing C, Kirches E, Mawrin C. Wilisch-Neumann A, et al. Among authors: kirches e. Clin Cancer Res. 2013 Oct 1;19(19):5402-12. doi: 10.1158/1078-0432.CCR-12-0299. Epub 2013 Aug 15. Clin Cancer Res. 2013. PMID: 23948974
102 results