Mann DJ - Search Results

1

A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division.

Martini S, Davis K, Faraway R, Elze L, Lockwood N, Jones A, Xie X, McDonald NQ, Mann DJ, Armstrong A, Ule J, Parker PJ. Martini S, et al. Among authors: mann dj. Nat Commun. 2021 Nov 26;12(1):6934. doi: 10.1038/s41467-021-27189-5. Nat Commun. 2021. PMID: 34836941 Free PMC article.

2

Kinetic template-guided tethering of fragments.

Nonoo RH, Armstrong A, Mann DJ. Nonoo RH, et al. Among authors: mann dj. ChemMedChem. 2012 Dec;7(12):2082-6. doi: 10.1002/cmdc.201200404. Epub 2012 Oct 2. ChemMedChem. 2012. PMID: 23033251

3

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.

Thinon E, Serwa RA, Broncel M, Brannigan JA, Brassat U, Wright MH, Heal WP, Wilkinson AJ, Mann DJ, Tate EW. Thinon E, et al. Among authors: mann dj. Nat Commun. 2014 Sep 26;5:4919. doi: 10.1038/ncomms5919. Nat Commun. 2014. PMID: 25255805 Free PMC article.

4

High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery.

Craven GB, Affron DP, Allen CE, Matthies S, Greener JG, Morgan RML, Tate EW, Armstrong A, Mann DJ. Craven GB, et al. Among authors: mann dj. Angew Chem Int Ed Engl. 2018 May 4;57(19):5257-5261. doi: 10.1002/anie.201711825. Epub 2018 Mar 26. Angew Chem Int Ed Engl. 2018. PMID: 29480525 Free PMC article.

5

Vinyl sulfonamide synthesis for irreversible tethering via a novel α-selenoether protection strategy.

Craven GB, Affron DP, Raymond PN, Mann DJ, Armstrong A. Craven GB, et al. Among authors: mann dj. Medchemcomm. 2018 Dec 13;10(1):158-163. doi: 10.1039/c8md00566d. eCollection 2019 Jan 1. Medchemcomm. 2018. PMID: 30774862 Free PMC article.

6

Multiparameter Kinetic Analysis for Covalent Fragment Optimization by Using Quantitative Irreversible Tethering (qIT).

Craven GB, Affron DP, Kösel T, Wong TLM, Jukes ZH, Liu CT, Morgan RML, Armstrong A, Mann DJ. Craven GB, et al. Among authors: mann dj. Chembiochem. 2020 Dec 1;21(23):3417-3422. doi: 10.1002/cbic.202000457. Epub 2020 Aug 7. Chembiochem. 2020. PMID: 32659037 Free PMC article.

7

Quantitative Irreversible Tethering (qIT) for Target-directed Covalent Fragment Screening.

Craven GB, Armstrong A, Mann DJ. Craven GB, et al. Among authors: mann dj. Bio Protoc. 2020 Dec 20;10(24):e3855. doi: 10.21769/BioProtoc.3855. eCollection 2020 Dec 20. Bio Protoc. 2020. PMID: 33659502 Free PMC article.

8

Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention.

Watson L, Soliman TN, Davis K, Kelly J, Lockwood N, Yang X, Lynham S, Scott JD, Crossland V, McDonald NQ, Mann DJ, Armstrong A, Eggert U, Parker PJ. Watson L, et al. Among authors: mann dj. Biochem J. 2021 Jun 25;478(12):2247-2263. doi: 10.1042/BCJ20210283. Biochem J. 2021. PMID: 34143863 Free PMC article.

9

Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.

Qin B, Craven GB, Hou P, Chesti J, Lu X, Child ES, Morgan RML, Niu W, Zhao L, Armstrong A, Mann DJ, Cui S. Qin B, et al. Among authors: mann dj. Acta Pharm Sin B. 2022 Oct;12(10):3924-3933. doi: 10.1016/j.apsb.2022.06.002. Epub 2022 Jun 9. Acta Pharm Sin B. 2022. PMID: 35702321 Free PMC article.

10

Covalent fragment libraries in drug discovery-Design, synthesis, and screening methods.

Hocking B, Armstrong A, Mann DJ. Hocking B, et al. Among authors: mann dj. Prog Med Chem. 2023;62:105-146. doi: 10.1016/bs.pmch.2023.10.003. Epub 2023 Nov 13. Prog Med Chem. 2023. PMID: 37981350

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