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A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells.
Oliveira MS, Barbosa MIF, de Souza TB, Moreira DRM, Martins FT, Villarreal W, Machado RP, Doriguetto AC, Soares MBP, Bezerra DP. Oliveira MS, et al. Among authors: villarreal w. Redox Biol. 2019 Jan;20:182-194. doi: 10.1016/j.redox.2018.10.006. Epub 2018 Oct 12. Redox Biol. 2019. PMID: 30359932 Free PMC article.
Cytotoxicity of Ru(II) piano-stool complexes with chloroquine and chelating ligands against breast and lung tumor cells: Interactions with DNA and BSA.
Colina-Vegas L, Villarreal W, Navarro M, de Oliveira CR, Graminha AE, Maia PIDS, Deflon VM, Ferreira AG, Cominetti MR, Batista AA. Colina-Vegas L, et al. Among authors: villarreal w. J Inorg Biochem. 2015 Dec;153:150-161. doi: 10.1016/j.jinorgbio.2015.07.016. Epub 2015 Jul 23. J Inorg Biochem. 2015. PMID: 26277415
Zinc-clotrimazole complexes are effective against Trichomonas vaginalis.
Midlej V, Rubim F, Villarreal W, Martins-Duarte ÉS, Navarro M, de Souza W, Benchimol M. Midlej V, et al. Among authors: villarreal w. Parasitology. 2019 Aug;146(9):1206-1216. doi: 10.1017/S003118201900043X. Epub 2019 May 3. Parasitology. 2019. PMID: 31046845
15 results