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A Phase II Study Evaluating Orteronel, an Inhibitor of Androgen Biosynthesis, in Patients With Androgen Receptor (AR)-Expressing Metastatic Breast Cancer (MBC).
Yardley DA, Young RR, Adelson KB, Silber AL, Najera JE, Daniel DB, Peacock N, Finney L, Hoekstra SJ, Shastry M, Hainsworth JD, Burris HA. Yardley DA, et al. Among authors: hoekstra sj. Clin Breast Cancer. 2022 Apr;22(3):269-278. doi: 10.1016/j.clbc.2021.10.011. Epub 2021 Oct 28. Clin Breast Cancer. 2022. PMID: 34824002 Clinical Trial.
Effect of combination treatment with zanoterone (WIN 49596), a steroidal androgen receptor antagonist, and finasteride (MK-906), a steroidal 5 alpha-reductase inhibitor, on the prostate and testes of beagle dogs.
Juniewicz PE, Hoekstra SJ, Lemp BM, Barbolt TA, Devin JA, Gauthier E, Frenette G, Dube JY, Tremblay RR. Juniewicz PE, et al. Among authors: hoekstra sj. Endocrinology. 1993 Aug;133(2):904-13. doi: 10.1210/endo.133.2.8393778. Endocrinology. 1993. PMID: 8393778