Bannister TD - Search Results

1

G protein signaling-biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists.

Stahl EL, Schmid CL, Acevedo-Canabal A, Read C, Grim TW, Kennedy NM, Bannister TD, Bohn LM. Stahl EL, et al. Among authors: bannister td. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2102178118. doi: 10.1073/pnas.2102178118. Proc Natl Acad Sci U S A. 2021. PMID: 34819362 Free PMC article.

2

Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.

Schmid CL, Kennedy NM, Ross NC, Lovell KM, Yue Z, Morgenweck J, Cameron MD, Bannister TD, Bohn LM. Schmid CL, et al. Among authors: bannister td. Cell. 2017 Nov 16;171(5):1165-1175.e13. doi: 10.1016/j.cell.2017.10.035. Cell. 2017. PMID: 29149605 Free PMC article.

3

Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119.

Nieto A, Fernández-Vega V, Spicer TP, Sturchler E, Adhikari P, Kennedy N, Mandat S, Chase P, Scampavia L, Bannister T, Hodder P, McDonald PH. Nieto A, et al. Assay Drug Dev Technol. 2018 Jul;16(5):278-288. doi: 10.1089/adt.2018.849. Assay Drug Dev Technol. 2018. PMID: 30019946 Free PMC article.

4

Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias.

Kennedy NM, Schmid CL, Ross NC, Lovell KM, Yue Z, Chen YT, Cameron MD, Bohn LM, Bannister TD. Kennedy NM, et al. Among authors: bannister td. J Med Chem. 2018 Oct 11;61(19):8895-8907. doi: 10.1021/acs.jmedchem.8b01136. Epub 2018 Sep 24. J Med Chem. 2018. PMID: 30199635 Free PMC article.

5

A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal.

Grim TW, Schmid CL, Stahl EL, Pantouli F, Ho JH, Acevedo-Canabal A, Kennedy NM, Cameron MD, Bannister TD, Bohn LM. Grim TW, et al. Among authors: bannister td. Neuropsychopharmacology. 2020 Jan;45(2):416-425. doi: 10.1038/s41386-019-0491-8. Epub 2019 Aug 23. Neuropsychopharmacology. 2020. PMID: 31443104 Free PMC article.

6

Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain.

Pantouli F, Grim TW, Schmid CL, Acevedo-Canabal A, Kennedy NM, Cameron MD, Bannister TD, Bohn LM. Pantouli F, et al. Among authors: bannister td. Neuropharmacology. 2021 Mar 1;185:108439. doi: 10.1016/j.neuropharm.2020.108439. Epub 2020 Dec 17. Neuropharmacology. 2021. PMID: 33345829 Free PMC article.

7

Identification of potent small molecule inhibitors of SARS-CoV-2 entry.

Mediouni S, Mou H, Otsuka Y, Jablonski JA, Adcock RS, Batra L, Chung DH, Rood C, de Vera IMS, Rahaim R Jr, Ullah S, Yu X, Getmanenko YA, Kennedy NM, Wang C, Nguyen TT, Hull M, Chen E, Bannister TD, Baillargeon P, Scampavia L, Farzan M, Valente ST, Spicer TP. Mediouni S, et al. Among authors: bannister td. SLAS Discov. 2022 Jan;27(1):8-19. doi: 10.1016/j.slasd.2021.10.012. Epub 2021 Oct 23. SLAS Discov. 2022. PMID: 35058179 Free PMC article.

8

Identification of Potential Modulators of the RGS7/Gβ5/R7BP Complex.

Stoveken HM, Fernandez-Vega V, Muntean BS, Patil DN, Shumate J, Bannister TD, Scampavia L, Spicer TP, Martemyanov KA. Stoveken HM, et al. Among authors: bannister td. SLAS Discov. 2021 Oct;26(9):1177-1188. doi: 10.1177/24725552211020679. Epub 2021 Jun 11. SLAS Discov. 2021. PMID: 34112017 Free PMC article.

9

The development of benzimidazoles as selective rho kinase inhibitors.

Sessions EH, Smolinski M, Wang B, Frackowiak B, Chowdhury S, Yin Y, Chen YT, Ruiz C, Lin L, Pocas J, Schröter T, Cameron MD, LoGrasso P, Feng Y, Bannister TD. Sessions EH, et al. Among authors: bannister td. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1939-43. doi: 10.1016/j.bmcl.2010.01.124. Epub 2010 Feb 1. Bioorg Med Chem Lett. 2010. PMID: 20167489

10

Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1.

Ting PY, Damoiseaux R, Titz B, Bradley KA, Graeber TG, Fernández-Vega V, Bannister TD, Chase P, Nair R, Scampavia L, Hodder P, Spicer TP, Colicelli J. Ting PY, et al. Among authors: bannister td. PLoS One. 2015 Mar 26;10(3):e0121833. doi: 10.1371/journal.pone.0121833. eCollection 2015. PLoS One. 2015. PMID: 25811598 Free PMC article.

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