Shen HM - Search Results

1

Loop extrusion promotes an alternate pathway for isotype switching.

Shen HM, Wuerffel R, Cantillo JF, Priyadarshi S, Lei X, Liang J, Wu YL, Kenter AL. Shen HM, et al. Cell Rep. 2021 Nov 23;37(8):110059. doi: 10.1016/j.celrep.2021.110059. Cell Rep. 2021. PMID: 34818547 Free PMC article.

2

Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney.

Shen HM, Bozek G, Pinkert CA, McBride K, Wang L, Kenter A, Storb U. Shen HM, et al. Mol Immunol. 2008 Apr;45(7):1883-92. doi: 10.1016/j.molimm.2007.10.041. Epub 2007 Dec 11. Mol Immunol. 2008. PMID: 18067961 Free PMC article.

3

Attracting AID to targets of somatic hypermutation.

Tanaka A, Shen HM, Ratnam S, Kodgire P, Storb U. Tanaka A, et al. Among authors: shen hm. J Exp Med. 2010 Feb 15;207(2):405-15. doi: 10.1084/jem.20090821. Epub 2010 Jan 25. J Exp Med. 2010. PMID: 20100870 Free PMC article.

4

Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice.

Shen HM, Tanaka A, Bozek G, Nicolae D, Storb U. Shen HM, et al. J Immunol. 2006 Oct 15;177(8):5386-92. doi: 10.4049/jimmunol.177.8.5386. J Immunol. 2006. PMID: 17015724

5

The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription.

Shen HM, Poirier MG, Allen MJ, North J, Lal R, Widom J, Storb U. Shen HM, et al. J Exp Med. 2009 May 11;206(5):1057-71. doi: 10.1084/jem.20082678. Epub 2009 Apr 20. J Exp Med. 2009. PMID: 19380635 Free PMC article.

6

Somatic hypermutation of immunoglobulin genes is linked to transcription.

Storb U, Peters A, Klotz E, Kim N, Shen HM, Kage K, Rogerson B, Martin TE. Storb U, et al. Among authors: shen hm. Curr Top Microbiol Immunol. 1998;229:11-9. doi: 10.1007/978-3-642-71984-4_2. Curr Top Microbiol Immunol. 1998. PMID: 9479844 Review. No abstract available.

7

The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes.

Shen HM, Cheo DL, Friedberg E, Storb U. Shen HM, et al. Mol Immunol. 1997 May;34(7):527-33. doi: 10.1016/s0161-5890(97)00064-3. Mol Immunol. 1997. PMID: 9364218

8

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

Shen HM, Peters A, Baron B, Zhu X, Storb U. Shen HM, et al. Science. 1998 Jun 12;280(5370):1750-2. doi: 10.1126/science.280.5370.1750. Science. 1998. PMID: 9624052

9

Somatic hypermutation: processivity of the cytosine deaminase AID and error-free repair of the resulting uracils.

Storb U, Shen HM, Nicolae D. Storb U, et al. Among authors: shen hm. Cell Cycle. 2009 Oct 1;8(19):3097-101. doi: 10.4161/cc.8.19.9658. Epub 2009 Oct 29. Cell Cycle. 2009. PMID: 19738437 No abstract available.

10

Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA.

Shen HM, Ratnam S, Storb U. Shen HM, et al. Mol Cell Biol. 2005 Dec;25(24):10815-21. doi: 10.1128/MCB.25.24.10815-10821.2005. Mol Cell Biol. 2005. PMID: 16314506 Free PMC article.

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