Deprez-Poulain R - Search Results

1

Identification of indole-based activators of insulin degrading enzyme.

Kraupner N, Dinh CP, Wen X, Landry V, Herledan A, Leroux F, Bosc D, Charton J, Maillard C, Warenghem S, Duplan I, Piveteau C, Hennuyer N, Staels B, Deprez B, Deprez-Poulain R. Kraupner N, et al. Among authors: deprez poulain r. Eur J Med Chem. 2022 Jan 15;228:113982. doi: 10.1016/j.ejmech.2021.113982. Epub 2021 Nov 16. Eur J Med Chem. 2022. PMID: 34815130

2

Synthesis and in vitro and in vivo antimalarial activity of N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine derivatives.

Ryckebusch A, Deprez-Poulain R, Maes L, Debreu-Fontaine MA, Mouray E, Grellier P, Sergheraert C. Ryckebusch A, et al. J Med Chem. 2003 Feb 13;46(4):542-57. doi: 10.1021/jm020960r. J Med Chem. 2003. PMID: 12570376

3

Facts, figures and trends in lead generation.

Deprez-Poulain R, Deprez B. Deprez-Poulain R, et al. Curr Top Med Chem. 2004;4(6):569-80. doi: 10.2174/1568026043451168. Curr Top Med Chem. 2004. PMID: 14965294 Review.

4

A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening.

Flipo M, Beghyn T, Charton J, Leroux VA, Deprez BP, Deprez-Poulain RF. Flipo M, et al. Bioorg Med Chem. 2007 Jan 1;15(1):63-76. doi: 10.1016/j.bmc.2006.10.010. Epub 2006 Oct 12. Bioorg Med Chem. 2007. PMID: 17070058

5

Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.

Flipo M, Beghyn T, Leroux V, Florent I, Deprez BP, Deprez-Poulain RF. Flipo M, et al. J Med Chem. 2007 Mar 22;50(6):1322-34. doi: 10.1021/jm061169b. Epub 2007 Feb 28. J Med Chem. 2007. PMID: 17326615

6

Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds.

Charton J, Charruault L, Deprez-Poulain R, Deprez B. Charton J, et al. Comb Chem High Throughput Screen. 2008 May;11(4):294-303. doi: 10.2174/138620708784246013. Comb Chem High Throughput Screen. 2008. PMID: 18473739

7

Natural compounds: leads or ideas? Bioinspired molecules for drug discovery.

Beghyn T, Deprez-Poulain R, Willand N, Folleas B, Deprez B. Beghyn T, et al. Chem Biol Drug Des. 2008 Jul;72(1):3-15. doi: 10.1111/j.1747-0285.2008.00673.x. Epub 2008 Jun 11. Chem Biol Drug Des. 2008. PMID: 18554253

8

Synthesis of a 200-member library of squaric acid N-hydroxylamide amides.

Charton J, Leroux F, Delaroche S, Landry V, Déprez BP, Déprez-Poulain RF. Charton J, et al. Bioorg Med Chem Lett. 2008 Sep 15;18(18):4968-71. doi: 10.1016/j.bmcl.2008.08.025. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18760922

9

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.

Charton J, Deprez-Poulain R, Hennuyer N, Tailleux A, Staels B, Deprez B. Charton J, et al. Bioorg Med Chem Lett. 2009 Jan 15;19(2):489-92. doi: 10.1016/j.bmcl.2008.11.040. Epub 2008 Nov 18. Bioorg Med Chem Lett. 2009. PMID: 19058965 Free article.

10

Synthetic EthR inhibitors boost antituberculous activity of ethionamide.

Willand N, Dirié B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Déprez-Poulain R, Delcroix G, Frénois F, Aumercier M, Locht C, Villeret V, Déprez B, Baulard AR. Willand N, et al. Nat Med. 2009 May;15(5):537-44. doi: 10.1038/nm.1950. Epub 2009 May 3. Nat Med. 2009. PMID: 19412174

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