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Xist nucleates local protein gradients to propagate silencing across the X chromosome.
Markaki Y, Gan Chong J, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schöneberg J, Heard E, Guttman M, Chou T, Plath K. Markaki Y, et al. Among authors: jachowicz jw. Cell. 2021 Dec 9;184(25):6174-6192.e32. doi: 10.1016/j.cell.2021.10.022. Epub 2021 Nov 4. Cell. 2021. PMID: 34813726 Free PMC article.
Single-cell measurement of higher-order 3D genome organization with scSPRITE.
Arrastia MV, Jachowicz JW, Ollikainen N, Curtis MS, Lai C, Quinodoz SA, Selck DA, Ismagilov RF, Guttman M. Arrastia MV, et al. Among authors: jachowicz jw. Nat Biotechnol. 2022 Jan;40(1):64-73. doi: 10.1038/s41587-021-00998-1. Epub 2021 Aug 23. Nat Biotechnol. 2022. PMID: 34426703 Free PMC article.
RNA promotes the formation of spatial compartments in the nucleus.
Quinodoz SA, Jachowicz JW, Bhat P, Ollikainen N, Banerjee AK, Goronzy IN, Blanco MR, Chovanec P, Chow A, Markaki Y, Thai J, Plath K, Guttman M. Quinodoz SA, et al. Among authors: jachowicz jw. Cell. 2021 Nov 11;184(23):5775-5790.e30. doi: 10.1016/j.cell.2021.10.014. Epub 2021 Nov 4. Cell. 2021. PMID: 34739832 Free PMC article.
Xist nucleates local protein gradients to propagate silencing across the X chromosome.
Markaki Y, Chong JG, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schӧneberg J, Heard E, Guttman M, Chou T, Plath K. Markaki Y, et al. Among authors: jachowicz jw. Cell. 2021 Dec 9;184(25):6212. doi: 10.1016/j.cell.2021.11.028. Cell. 2021. PMID: 34890555 Free PMC article. No abstract available.
15 results