Tian J - Search Results

1

Optimized process operations reduce product retention and column clogging in ATF-based perfusion cell cultures.

Su Y, Wei Z, Miao Y, Sun L, Shen Y, Tang Z, Li L, Quan Y, Yu H, Wang WC, Zhou W, Tian J. Su Y, et al. Among authors: tian j. Appl Microbiol Biotechnol. 2021 Dec;105(24):9125-9136. doi: 10.1007/s00253-021-11662-8. Epub 2021 Nov 23. Appl Microbiol Biotechnol. 2021. PMID: 34811605

2

Comparative study of therapeutic antibody candidates derived from mini-pool and clonal cell lines.

Fan L, Rizzi G, Bierilo K, Tian J, Yee JC, Russell R, Das TK. Fan L, et al. Among authors: tian j. Biotechnol Prog. 2017 Nov;33(6):1456-1462. doi: 10.1002/btpr.2477. Epub 2017 May 2. Biotechnol Prog. 2017. PMID: 28393481

3

Modulating and optimizing Pluronic F-68 concentrations and feeding for intensified perfusion Chinese hamster ovary cell cultures.

Wei Z, Xia Y, Su Y, Quan Y, Sun L, Wang S, Zhu F, Chen Z, Tian J, Wang WC, Zhou W, Yu H. Wei Z, et al. Among authors: tian j. Biotechnol Prog. 2023 Jul-Aug;39(4):e3340. doi: 10.1002/btpr.3340. Epub 2023 Mar 27. Biotechnol Prog. 2023. PMID: 36970759

4

Developing an ultra-intensified fed-batch cell culture process with greatly improved performance and productivity.

Xiang S, Zhang J, Yu L, Tian J, Tang W, Tang H, Xu K, Wang X, Cui Y, Ren K, Cao W, Su Y, Zhou W. Xiang S, et al. Among authors: tian j. Biotechnol Bioeng. 2024 Feb;121(2):696-709. doi: 10.1002/bit.28605. Epub 2023 Nov 23. Biotechnol Bioeng. 2024. PMID: 37994547

5

Modulating cell culture oxidative stress reduces protein glycation and acidic charge variant formation.

Chung S, Tian J, Tan Z, Chen J, Zhang N, Huang Y, Vandermark E, Lee J, Borys M, Li ZJ. Chung S, et al. Among authors: tian j. MAbs. 2019 Jan;11(1):205-216. doi: 10.1080/19420862.2018.1537533. Epub 2019 Jan 3. MAbs. 2019. PMID: 30602334 Free PMC article.

6

Process intensification in fed-batch production bioreactors using non-perfusion seed cultures.

Yongky A, Xu J, Tian J, Oliveira C, Zhao J, McFarland K, Borys MC, Li ZJ. Yongky A, et al. Among authors: tian j. MAbs. 2019 Nov-Dec;11(8):1502-1514. doi: 10.1080/19420862.2019.1652075. Epub 2019 Aug 19. MAbs. 2019. PMID: 31379298 Free PMC article.

7

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media.

Xu J, Rehmann MS, Xu X, Huang C, Tian J, Qian NX, Li ZJ. Xu J, et al. Among authors: tian j. MAbs. 2018 Apr;10(3):488-499. doi: 10.1080/19420862.2018.1433978. Epub 2018 Feb 20. MAbs. 2018. PMID: 29388872 Free PMC article.

8

Industrial bioprocessing perspectives on managing therapeutic protein charge variant profiles.

Chung S, Tian J, Tan Z, Chen J, Lee J, Borys M, Li ZJ. Chung S, et al. Among authors: tian j. Biotechnol Bioeng. 2018 Jul;115(7):1646-1665. doi: 10.1002/bit.26587. Epub 2018 Mar 31. Biotechnol Bioeng. 2018. PMID: 29532901 Review.

9

High throughput screening data for a case study of CHO cell culture process development.

He Q, Xu J, Vandermark E, Tian J, Qian Y, Chelius C, Lee J, Borys MC, Li ZJ, Pendse G. He Q, et al. Among authors: tian j. Data Brief. 2021 Oct 17;39:107491. doi: 10.1016/j.dib.2021.107491. eCollection 2021 Dec. Data Brief. 2021. PMID: 34712760 Free PMC article.

10

Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines.

Tian J, He Q, Oliveira C, Qian Y, Egan S, Xu J, Qian NX, Langsdorf E, Warrack B, Aranibar N, Reily M, Borys M, Li ZJ. Tian J, et al. Eng Life Sci. 2020 Jan 9;20(3-4):112-125. doi: 10.1002/elsc.201900124. eCollection 2020 Mar. Eng Life Sci. 2020. PMID: 32874175 Free PMC article.

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