Shihabuddin LS - Search Results

1

Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson's disease enrolled in PPMI.

Huh YE, Park H, Chiang MSR, Tuncali I, Liu G, Locascio JJ, Shirvan J, Hutten SJ, Rotunno MS, Viel C, Shihabuddin LS, Wang B, Sardi SP, Scherzer CR. Huh YE, et al. Among authors: shihabuddin ls. NPJ Parkinsons Dis. 2021 Nov 22;7(1):102. doi: 10.1038/s41531-021-00241-3. NPJ Parkinsons Dis. 2021. PMID: 34811369 Free PMC article.

2

Cerebrospinal fluid proteomics implicates the granin family in Parkinson's disease.

Rotunno MS, Lane M, Zhang W, Wolf P, Oliva P, Viel C, Wills AM, Alcalay RN, Scherzer CR, Shihabuddin LS, Zhang K, Sardi SP. Rotunno MS, et al. Among authors: shihabuddin ls. Sci Rep. 2020 Feb 12;10(1):2479. doi: 10.1038/s41598-020-59414-4. Sci Rep. 2020. PMID: 32051502 Free PMC article.

3

No evidence for substrate accumulation in Parkinson brains with GBA mutations.

Gegg ME, Sweet L, Wang BH, Shihabuddin LS, Sardi SP, Schapira AH. Gegg ME, et al. Among authors: shihabuddin ls. Mov Disord. 2015 Jul;30(8):1085-9. doi: 10.1002/mds.26278. Epub 2015 Jun 11. Mov Disord. 2015. PMID: 26096906 Free PMC article.

4

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

Sardi SP, Viel C, Clarke J, Treleaven CM, Richards AM, Park H, Olszewski MA, Dodge JC, Marshall J, Makino E, Wang B, Sidman RL, Cheng SH, Shihabuddin LS. Sardi SP, et al. Among authors: shihabuddin ls. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2699-2704. doi: 10.1073/pnas.1616152114. Epub 2017 Feb 21. Proc Natl Acad Sci U S A. 2017. PMID: 28223512 Free PMC article.

5

Viral delivery of a microRNA to Gba to the mouse central nervous system models neuronopathic Gaucher disease.

Jackson KL, Viel C, Clarke J, Bu J, Chan M, Wang B, Shihabuddin LS, Sardi SP. Jackson KL, et al. Among authors: shihabuddin ls. Neurobiol Dis. 2019 Oct;130:104513. doi: 10.1016/j.nbd.2019.104513. Epub 2019 Jun 21. Neurobiol Dis. 2019. PMID: 31233883 Free article.

6

Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model.

Viel C, Clarke J, Kayatekin C, Richards AM, Chiang MSR, Park H, Wang B, Shihabuddin LS, Sardi SP. Viel C, et al. Among authors: shihabuddin ls. Sci Rep. 2021 Oct 22;11(1):20945. doi: 10.1038/s41598-021-00404-5. Sci Rep. 2021. PMID: 34686711 Free PMC article.

7

Murine Models of Lysosomal Storage Diseases Exhibit Differences in Brain Protein Aggregation and Neuroinflammation.

Clarke J, Kayatekin C, Viel C, Shihabuddin L, Sardi SP. Clarke J, et al. Biomedicines. 2021 Apr 21;9(5):446. doi: 10.3390/biomedicines9050446. Biomedicines. 2021. PMID: 33919140 Free PMC article.

8

Sardi SP, Cheng SH, Shihabuddin LS. Sardi SP, et al. Among authors: shihabuddin ls. Prog Neurobiol. 2015 Feb;125:47-62. doi: 10.1016/j.pneurobio.2014.12.001. Epub 2015 Jan 6. Prog Neurobiol. 2015. PMID: 25573151 Free article. Review.

9

New Frontiers in Parkinson's Disease: From Genetics to the Clinic.

Shihabuddin LS, Brundin P, Greenamyre JT, Stephenson D, Sardi SP. Shihabuddin LS, et al. J Neurosci. 2018 Oct 31;38(44):9375-9382. doi: 10.1523/JNEUROSCI.1666-18.2018. J Neurosci. 2018. PMID: 30381429 Free PMC article. Review.

10

Sterol auto-oxidation adversely affects human motor neuron viability and is a neuropathological feature of amyotrophic lateral sclerosis.

Dodge JC, Yu J, Sardi SP, Shihabuddin LS. Dodge JC, et al. Among authors: shihabuddin ls. Sci Rep. 2021 Jan 12;11(1):803. doi: 10.1038/s41598-020-80378-y. Sci Rep. 2021. PMID: 33436868 Free PMC article.

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