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The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders.
Alkelai A, Greenbaum L, Docherty AR, Shabalin AA, Povysil G, Malakar A, Hughes D, Delaney SL, Peabody EP, McNamara J, Gelfman S, Baugh EH, Zoghbi AW, Harms MB, Hwang HS, Grossman-Jonish A, Aggarwal V, Heinzen EL, Jobanputra V, Pulver AE, Lerer B, Goldstein DB. Alkelai A, et al. Among authors: zoghbi aw. Mol Psychiatry. 2022 Mar;27(3):1435-1447. doi: 10.1038/s41380-021-01383-9. Epub 2021 Nov 19. Mol Psychiatry. 2022. PMID: 34799694
Exome sequencing in obsessive-compulsive disorder reveals a burden of rare damaging coding variants.
Halvorsen M, Samuels J, Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller DA, Knowles JA, Zoghbi AW, Pottinger TD, Grados MA, Riddle MA, Bienvenu OJ, Nestadt PS, Krasnow J, Goes FS, Maher B, Nestadt G, Goldstein DB. Halvorsen M, et al. Among authors: zoghbi aw. Nat Neurosci. 2021 Aug;24(8):1071-1076. doi: 10.1038/s41593-021-00876-8. Epub 2021 Jun 28. Nat Neurosci. 2021. PMID: 34183866
High-impact rare genetic variants in severe schizophrenia.
Zoghbi AW, Dhindsa RS, Goldberg TE, Mehralizade A, Motelow JE, Wang X, Alkelai A, Harms MB, Lieberman JA, Markx S, Goldstein DB. Zoghbi AW, et al. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2112560118. doi: 10.1073/pnas.2112560118. Proc Natl Acad Sci U S A. 2021. PMID: 34903660 Free PMC article.
Pharmacogenomic insights in psychiatric care: uncovering novel actionability, allele-specific CYP2D6 copy number variation, and phenoconversion in 15,000 patients.
Patel JN, Morris SA, Torres R, Rhead B, Vlangos C, Mueller DJ, Brown LC, Lefkofsky H, Ali M, De La Vega FM, Barnes KC, Zoghbi A, Stanton JD, Badgeley MA. Patel JN, et al. Mol Psychiatry. 2024 Nov;29(11):3495-3502. doi: 10.1038/s41380-024-02588-4. Epub 2024 May 23. Mol Psychiatry. 2024. PMID: 38783055 Free PMC article.
18 results