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Page 1
The senescent cell epigenome.
Yang N, Sen P. Yang N, et al. Among authors: sen p. Aging (Albany NY). 2018 Nov 3;10(11):3590-3609. doi: 10.18632/aging.101617. Aging (Albany NY). 2018. PMID: 30391936 Free PMC article. Review.
The eroding chromatin landscape of aging stem cells.
Shi C, Wang L, Sen P. Shi C, et al. Among authors: sen p. Transl Med Aging. 2020;4:121-131. doi: 10.1016/j.tma.2020.08.002. Epub 2020 Aug 17. Transl Med Aging. 2020. PMID: 33024907 Free PMC article.
Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis.
Herman AB, Anerillas C, Harris SC, Munk R, Martindale JL, Yang X, Mazan-Mamczarz K, Zhang Y, Heckenbach IJ, Scheibye-Knudsen M, De S, Sen P, Abdelmohsen K, Gorospe M. Herman AB, et al. Among authors: sen p. Nucleic Acids Res. 2021 Jul 21;49(13):7389-7405. doi: 10.1093/nar/gkab538. Nucleic Acids Res. 2021. PMID: 34181735 Free PMC article.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: sen p. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528512. doi: 10.1101/2023.02.14.528512. bioRxiv. 2023. Update in: Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005 PMID: 36824822 Free PMC article. Updated. Preprint.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, deCabo R, Sidoli S, Sen P. Occean JR, et al. Among authors: sen p. bioRxiv [Preprint]. 2024 Jul 3:2023.02.15.528714. doi: 10.1101/2023.02.15.528714. bioRxiv. 2024. Update in: Nat Commun. 2024 Jul 28;15(1):6357. doi: 10.1038/s41467-024-50725-y PMID: 36824863 Free PMC article. Updated. Preprint.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: sen p. Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116496 Free PMC article.
Understanding cardiac senescence one cell type at a time.
Sen P, Gurha P. Sen P, et al. J Cardiovasc Aging. 2023 May;3(2):22. doi: 10.20517/jca.2023.16. Epub 2023 May 4. J Cardiovasc Aging. 2023. PMID: 37273661 Free PMC article. No abstract available.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, de Cabo R, Sidoli S, Sen P. Occean JR, et al. Among authors: sen p. Nat Commun. 2024 Jul 28;15(1):6357. doi: 10.1038/s41467-024-50725-y. Nat Commun. 2024. PMID: 39069555 Free PMC article.
1,555 results