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Page 1
Cell-type specialization is encoded by specific chromatin topologies.
Winick-Ng W, Kukalev A, Harabula I, Zea-Redondo L, Szabó D, Meijer M, Serebreni L, Zhang Y, Bianco S, Chiariello AM, Irastorza-Azcarate I, Thieme CJ, Sparks TM, Carvalho S, Fiorillo L, Musella F, Irani E, Torlai Triglia E, Kolodziejczyk AA, Abentung A, Apostolova G, Paul EJ, Franke V, Kempfer R, Akalin A, Teichmann SA, Dechant G, Ungless MA, Nicodemi M, Welch L, Castelo-Branco G, Pombo A. Winick-Ng W, et al. Nature. 2021 Nov;599(7886):684-691. doi: 10.1038/s41586-021-04081-2. Epub 2021 Nov 17. Nature. 2021. PMID: 34789882 Free PMC article.
Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping.
Fan R, Zhang D, Rodríguez-Kirby L, Lin Y, Song M, Wang L, Wang L, Kanatani S, Jimenez-Beristain T, Dang Y, Zhong M, Kukanja P, Wang S, Chen X, Gao F, Wang D, Xu H, Lou X, Liu Y, Chen J, Sestan N, Uhlen P, Kriegstein AR, Zhao H, Castelo-Branco G. Fan R, et al. Among authors: castelo branco g. Res Sq [Preprint]. 2024 Aug 12:rs.3.rs-4814866. doi: 10.21203/rs.3.rs-4814866/v1. Res Sq. 2024. PMID: 39184075 Free PMC article. Preprint.
Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping.
Zhang D, Rubio Rodríguez-Kirby LA, Lin Y, Song M, Wang L, Wang L, Kanatani S, Jimenez-Beristain T, Dang Y, Zhong M, Kukanja P, Wang S, Chen XL, Gao F, Wang D, Xu H, Lou X, Liu Y, Chen J, Sestan N, Uhlén P, Kriegstein A, Zhao H, Castelo-Branco G, Fan R. Zhang D, et al. Among authors: castelo branco g. bioRxiv [Preprint]. 2024 Jul 28:2024.07.28.605493. doi: 10.1101/2024.07.28.605493. bioRxiv. 2024. PMID: 39091821 Free PMC article. Preprint.
Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.
Andäng M, Hjerling-Leffler J, Moliner A, Lundgren TK, Castelo-Branco G, Nanou E, Pozas E, Bryja V, Halliez S, Nishimaru H, Wilbertz J, Arenas E, Koltzenburg M, Charnay P, El Manira A, Ibañez CF, Ernfors P. Andäng M, et al. Nature. 2008 Jan 24;451(7177):460-4. doi: 10.1038/nature06488. Epub 2008 Jan 9. Nature. 2008. PMID: 18185516
Citrullination regulates pluripotency and histone H1 binding to chromatin.
Christophorou MA, Castelo-Branco G, Halley-Stott RP, Oliveira CS, Loos R, Radzisheuskaya A, Mowen KA, Bertone P, Silva JC, Zernicka-Goetz M, Nielsen ML, Gurdon JB, Kouzarides T. Christophorou MA, et al. Nature. 2014 Mar 6;507(7490):104-8. doi: 10.1038/nature12942. Epub 2014 Jan 26. Nature. 2014. PMID: 24463520 Free PMC article.
RNA velocity of single cells.
La Manno G, Soldatov R, Zeisel A, Braun E, Hochgerner H, Petukhov V, Lidschreiber K, Kastriti ME, Lönnerberg P, Furlan A, Fan J, Borm LE, Liu Z, van Bruggen D, Guo J, He X, Barker R, Sundström E, Castelo-Branco G, Cramer P, Adameyko I, Linnarsson S, Kharchenko PV. La Manno G, et al. Nature. 2018 Aug;560(7719):494-498. doi: 10.1038/s41586-018-0414-6. Epub 2018 Aug 8. Nature. 2018. PMID: 30089906 Free PMC article.
Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis.
Falcão AM, van Bruggen D, Marques S, Meijer M, Jäkel S, Agirre E, Samudyata, Floriddia EM, Vanichkina DP, Ffrench-Constant C, Williams A, Guerreiro-Cacais AO, Castelo-Branco G. Falcão AM, et al. Nat Med. 2018 Dec;24(12):1837-1844. doi: 10.1038/s41591-018-0236-y. Epub 2018 Nov 12. Nat Med. 2018. PMID: 30420755 Free PMC article.
Altered human oligodendrocyte heterogeneity in multiple sclerosis.
Jäkel S, Agirre E, Mendanha Falcão A, van Bruggen D, Lee KW, Knuesel I, Malhotra D, Ffrench-Constant C, Williams A, Castelo-Branco G. Jäkel S, et al. Nature. 2019 Feb;566(7745):543-547. doi: 10.1038/s41586-019-0903-2. Epub 2019 Jan 23. Nature. 2019. PMID: 30747918 Free PMC article.
RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions.
Bonetti A, Agostini F, Suzuki AM, Hashimoto K, Pascarella G, Gimenez J, Roos L, Nash AJ, Ghilotti M, Cameron CJF, Valentine M, Medvedeva YA, Noguchi S, Agirre E, Kashi K, Samudyata, Luginbühl J, Cazzoli R, Agrawal S, Luscombe NM, Blanchette M, Kasukawa T, Hoon M, Arner E, Lenhard B, Plessy C, Castelo-Branco G, Orlando V, Carninci P. Bonetti A, et al. Nat Commun. 2020 Feb 24;11(1):1018. doi: 10.1038/s41467-020-14337-6. Nat Commun. 2020. PMID: 32094342 Free PMC article.
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury.
Floriddia EM, Lourenço T, Zhang S, van Bruggen D, Hilscher MM, Kukanja P, Gonçalves Dos Santos JP, Altınkök M, Yokota C, Llorens-Bobadilla E, Mulinyawe SB, Grãos M, Sun LO, Frisén J, Nilsson M, Castelo-Branco G. Floriddia EM, et al. Nat Commun. 2020 Nov 17;11(1):5860. doi: 10.1038/s41467-020-19453-x. Nat Commun. 2020. PMID: 33203872 Free PMC article.
73 results