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Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer.
Clin Cancer Res. 2022 Feb 15;28(4):708-718. doi: 10.1158/1078-0432.CCR-20-4116.
Clin Cancer Res. 2022.
PMID: 34789479
Free PMC article.
PDX-derived organoids model in vivo drug response and secrete biomarkers.
Huang L, Bockorny B, Paul I, Akshinthala D, Frappart PO, Gandarilla O, Bose A, Sanchez-Gonzalez V, Rouse EE, Lehoux SD, Pandell N, Lim CM, Clohessy JG, Grossman J, Gonzalez R, Del Pino SP, Daaboul G, Sawhney MS, Freedman SD, Kleger A, Cummings RD, Emili A, Muthuswamy LB, Hidalgo M, Muthuswamy SK.
Huang L, et al. Among authors: akshinthala d.
JCI Insight. 2020 Nov 5;5(21):e135544. doi: 10.1172/jci.insight.135544.
JCI Insight. 2020.
PMID: 32990680
Free PMC article.
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Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids.
Huang L, Desai R, Conrad DN, Leite NC, Akshinthala D, Lim CM, Gonzalez R, Muthuswamy LB, Gartner Z, Muthuswamy SK.
Huang L, et al. Among authors: akshinthala d.
Cell Stem Cell. 2021 Jun 3;28(6):1090-1104.e6. doi: 10.1016/j.stem.2021.03.022. Epub 2021 Apr 28.
Cell Stem Cell. 2021.
PMID: 33915081
Free PMC article.
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Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids.
Meng Q, Xie S, Gray GK, Dezfulian MH, Li W, Huang L, Akshinthala D, Ferrer E, Conahan C, Perea Del Pino S, Grossman J, Elledge SJ, Hidalgo M, Muthuswamy SK.
Meng Q, et al. Among authors: akshinthala d.
J Immunother Cancer. 2021 Nov;9(11):e003213. doi: 10.1136/jitc-2021-003213.
J Immunother Cancer. 2021.
PMID: 34789550
Free PMC article.
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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Koikawa K, Kibe S, Suizu F, Sekino N, Kim N, Manz TD, Pinch BJ, Akshinthala D, Verma A, Gaglia G, Nezu Y, Ke S, Qiu C, Ohuchida K, Oda Y, Lee TH, Wegiel B, Clohessy JG, London N, Santagata S, Wulf GM, Hidalgo M, Muthuswamy SK, Nakamura M, Gray NS, Zhou XZ, Lu KP.
Koikawa K, et al. Among authors: akshinthala d.
Cell. 2021 Sep 2;184(18):4753-4771.e27. doi: 10.1016/j.cell.2021.07.020. Epub 2021 Aug 12.
Cell. 2021.
PMID: 34388391
Free PMC article.
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Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer.
Oliphant MUJ, Akshinthala D, Muthuswamy SK.
Oliphant MUJ, et al. Among authors: akshinthala d.
Breast Cancer Res. 2024 Mar 29;26(1):56. doi: 10.1186/s13058-024-01798-6.
Breast Cancer Res. 2024.
PMID: 38553763
Free PMC article.
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Establishing conditions for the generation and maintenance of estrogen receptor-positive organoid models of breast cancer.
Oliphant MU, Akshinthala D, Muthuswamy SK.
Oliphant MU, et al. Among authors: akshinthala d.
Res Sq [Preprint]. 2023 Oct 4:rs.3.rs-3341539. doi: 10.21203/rs.3.rs-3341539/v1.
Res Sq. 2023.
Update in:
Breast Cancer Res. 2024 Mar 29;26(1):56. doi: 10.1186/s13058-024-01798-6.
PMID: 37886440
Free PMC article.
Updated.
Preprint.
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