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Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models.
Singh S, Quarni W, Goralski M, Wan S, Jin H, Van de Velde LA, Fang J, Wu Q, Abu-Zaid A, Wang T, Singh R, Craft D, Fan Y, Confer T, Johnson M, Akers WJ, Wang R, Murray PJ, Thomas PG, Nijhawan D, Davidoff AM, Yang J. Singh S, et al. Among authors: davidoff am. Sci Adv. 2021 Nov 19;7(47):eabj5405. doi: 10.1126/sciadv.abj5405. Epub 2021 Nov 17. Sci Adv. 2021. PMID: 34788094 Free PMC article.
KDM5A Regulates a Translational Program that Controls p53 Protein Expression.
Hu D, Jablonowski C, Cheng PH, AlTahan A, Li C, Wang Y, Palmer L, Lan C, Sun B, Abu-Zaid A, Fan Y, Brimble M, Gamboa NT, Kumbhar RC, Yanishevski D, Miller KM, Kang G, Zambetti GP, Chen T, Yan Q, Davidoff AM, Yang J. Hu D, et al. Among authors: davidoff am. iScience. 2018 Nov 30;9:84-100. doi: 10.1016/j.isci.2018.10.012. Epub 2018 Oct 17. iScience. 2018. PMID: 30388705 Free PMC article.
17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma.
Singh S, Abu-Zaid A, Lin W, Low J, Abdolvahabi A, Jin H, Wu Q, Cooke B, Fang J, Bowling J, Vaithiyalingam S, Currier D, Yun MK, Fernando DM, Maier J, Tillman H, Bulsara P, Lu Z, Das S, Shelat A, Li Z, Young B, Lee R, Rankovic Z, Murphy AJ, White SW, Davidoff AM, Chen T, Yang J. Singh S, et al. Among authors: davidoff am. iScience. 2020 Dec 28;24(1):101996. doi: 10.1016/j.isci.2020.101996. eCollection 2021 Jan 22. iScience. 2020. PMID: 33490904 Free PMC article.
Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps.
Brimble MA, Cheng PH, Winston SM, Reeves IL, Souquette A, Spence Y, Zhou J, Wang YD, Morton CL, Valentine M, Thomas PG, Nathwani AC, Gray JT, Davidoff AM. Brimble MA, et al. Among authors: davidoff am. Mol Ther Methods Clin Dev. 2022 Jan 19;24:280-291. doi: 10.1016/j.omtm.2022.01.008. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35211640 Free PMC article.
389 results