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Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units.
Charalampous T, Alcolea-Medina A, Snell LB, Williams TGS, Batra R, Alder C, Telatin A, Camporota L, Meadows CIS, Wyncoll D, Barrett NA, Hemsley CJ, Bryan L, Newsholme W, Boyd SE, Green A, Mahadeva U, Patel A, Cliff PR, Page AJ, O'Grady J, Edgeworth JD. Charalampous T, et al. Among authors: williams tgs. Genome Med. 2021 Nov 17;13(1):182. doi: 10.1186/s13073-021-00991-y. Genome Med. 2021. PMID: 34784976 Free PMC article.
Co-infection in critically ill patients with COVID-19: an observational cohort study from England.
Baskaran V, Lawrence H, Lansbury LE, Webb K, Safavi S, Zainuddin NI, Huq T, Eggleston C, Ellis J, Thakker C, Charles B, Boyd S, Williams T, Phillips C, Redmore E, Platt S, Hamilton E, Barr A, Venyo L, Wilson P, Bewick T, Daniel P, Dark P, Jeans AR, McCanny J, Edgeworth JD, Llewelyn MJ, Schmid ML, McKeever TM, Beed M, Lim WS. Baskaran V, et al. J Med Microbiol. 2021 Apr;70(4):001350. doi: 10.1099/jmm.0.001350. J Med Microbiol. 2021. PMID: 33861190 Free PMC article.
SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study.
Stirrup O, Boshier F, Venturini C, Guerra-Assunção JA, Alcolea-Medina A, Beckett A, Charalampous T, da Silva Filipe A, Glaysher S, Khan T, Kulasegaran Shylini R, Kele B, Monahan I, Mollett G, Parker M, Pelosi E, Randell P, Roy S, Taylor J, Weller S, Wilson-Davies E, Wade P, Williams R; COG-UK-HOCI Variant substudy consortium; COVID-19 Genomics UK (COG-UK) consortium; Copas A, Cutino-Moguel MT, Freemantle N, Hayward AC, Holmes A, Hughes J, Mahungu T, Nebbia G, Partridge D, Pope C, Price J, Robson S, Saeed K, de Silva T, Snell L, Thomson E, Witney AA, Breuer J. Stirrup O, et al. BMJ Open Respir Res. 2021 Sep;8(1):e001029. doi: 10.1136/bmjresp-2021-001029. BMJ Open Respir Res. 2021. PMID: 34544733 Free PMC article.
Feasibility and clinical utility of local rapid Nanopore influenza A virus whole genome sequencing for integrated outbreak management, genotypic resistance detection and timely surveillance.
Williams TGS, Snell LB, Alder C, Charalampous T, Alcolea-Medina A, Sehmi JK, Al-Yaakoubi N, Humayun G, Miah S, Lackenby A, Zambon M, Batra R, Douthwaite S, Edgeworth JD, Nebbia G. Williams TGS, et al. Microb Genom. 2023 Aug;9(8):mgen001083. doi: 10.1099/mgen.0.001083. Microb Genom. 2023. PMID: 37590039 Free PMC article.
Routine Metagenomics Service for ICU Patients with Respiratory Infection.
Charalampous T, Alcolea-Medina A, Snell LB, Alder C, Tan M, Williams TGS, Al-Yaakoubi N, Humayun G, Meadows CIS, Wyncoll DLA, Paul R, Hemsley CJ, Jeyaratnam D, Newsholme W, Goldenberg S, Patel A, Tucker F, Nebbia G, Wilks M, Chand M, Cliff PR, Batra R, O'Grady J, Barrett NA, Edgeworth JD. Charalampous T, et al. Among authors: williams tgs. Am J Respir Crit Care Med. 2024 Jan 15;209(2):164-174. doi: 10.1164/rccm.202305-0901OC. Am J Respir Crit Care Med. 2024. PMID: 37938162 Free PMC article.
A Multinational Case Series Describing Successful Treatment of Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection Caused by Omicron Sublineages With Prolonged Courses of Nirmatrelvir/Ritonavir.
Snell LB, McGreal-Bellone A, Nye C, Gage S, Bakrania P, Williams TGS, Aarons E, Botgros A, Douthwaite ST, Mallon P, Milligan I, Moore C, O'Kelly B, Underwood J, de Barra E, Nebbia G. Snell LB, et al. Among authors: williams tgs. Open Forum Infect Dis. 2023 Dec 7;11(1):ofad612. doi: 10.1093/ofid/ofad612. eCollection 2024 Jan. Open Forum Infect Dis. 2023. PMID: 38269048 Free PMC article.
Unified metagenomic method for rapid detection of microorganisms in clinical samples.
Alcolea-Medina A, Alder C, Snell LB, Charalampous T, Aydin A, Nebbia G, Williams T, Goldenberg S, Douthwaite S, Batra R, Cliff PR, Mischo H, Neil S, Wilks M, Edgeworth JD. Alcolea-Medina A, et al. Commun Med (Lond). 2024 Jul 7;4(1):135. doi: 10.1038/s43856-024-00554-3. Commun Med (Lond). 2024. PMID: 38972920 Free PMC article.
Publisher Correction: Unified metagenomic method for rapid detection of microorganisms in clinical samples.
Alcolea-Medina A, Alder C, Snell LB, Charalampous T, Aydin A, Nebbia G, Williams T, Goldenberg S, Douthwaite S, Batra R, Cliff PR, Mischo H, Neil S, Wilks M, Edgeworth JD. Alcolea-Medina A, et al. Commun Med (Lond). 2024 Jul 26;4(1):151. doi: 10.1038/s43856-024-00579-8. Commun Med (Lond). 2024. PMID: 39060434 Free PMC article. No abstract available.
23 results