Lowe D - Search Results

1

Dendritic cell vaccines targeting tumor blood vessel antigens in combination with dasatinib induce therapeutic immune responses in patients with checkpoint-refractory advanced melanoma.

Storkus WJ, Maurer D, Lin Y, Ding F, Bose A, Lowe D, Rose A, DeMark M, Karapetyan L, Taylor JL, Chelvanambi M, Fecek RJ, Filderman JN, Looney TJ, Miller L, Linch E, Lowman GM, Kalinski P, Butterfield LH, Tarhini A, Tawbi H, Kirkwood JM. Storkus WJ, et al. Among authors: lowe d. J Immunother Cancer. 2021 Nov;9(11):e003675. doi: 10.1136/jitc-2021-003675. J Immunother Cancer. 2021. PMID: 34782430 Free PMC article. Clinical Trial.

2

Extranodal induction of therapeutic immunity in the tumor microenvironment after intratumoral delivery of Tbet gene-modified dendritic cells.

Chen L, Taylor JL, Sabins NC, Lowe DB, Qu Y, You Z, Storkus WJ. Chen L, et al. Among authors: lowe db. Cancer Gene Ther. 2013 Aug;20(8):469-77. doi: 10.1038/cgt.2013.42. Epub 2013 Jul 12. Cancer Gene Ther. 2013. PMID: 23846252 Free PMC article.

3

Intratumoral IL-12 gene therapy results in the crosspriming of Tc1 cells reactive against tumor-associated stromal antigens.

Zhao X, Bose A, Komita H, Taylor JL, Kawabe M, Chi N, Spokas L, Lowe DB, Goldbach C, Alber S, Watkins SC, Butterfield LH, Kalinski P, Kirkwood JM, Storkus WJ. Zhao X, et al. Mol Ther. 2011 Apr;19(4):805-14. doi: 10.1038/mt.2010.295. Epub 2010 Dec 28. Mol Ther. 2011. PMID: 21189473 Free PMC article.

4

Chronic inflammation and immunologic-based constraints in malignant disease.

Lowe DB, Storkus WJ. Lowe DB, et al. Immunotherapy. 2011 Oct;3(10):1265-74. doi: 10.2217/imt.11.113. Immunotherapy. 2011. PMID: 21995576 Free PMC article. Review.

5

Combined Tbet and IL12 gene therapy elicits and recruits superior antitumor immunity in vivo.

Qu Y, Chen L, Lowe DB, Storkus WJ, Taylor JL. Qu Y, et al. Mol Ther. 2012 Mar;20(3):644-51. doi: 10.1038/mt.2011.283. Epub 2012 Jan 3. Mol Ther. 2012. PMID: 22215017 Free PMC article.

6

Vaccines targeting tumor blood vessel antigens promote CD8(+) T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice.

Zhao X, Bose A, Komita H, Taylor JL, Chi N, Lowe DB, Okada H, Cao Y, Mukhopadhyay D, Cohen PA, Storkus WJ. Zhao X, et al. Among authors: lowe db. J Immunol. 2012 Feb 15;188(4):1782-8. doi: 10.4049/jimmunol.1101644. Epub 2012 Jan 13. J Immunol. 2012. PMID: 22246626 Free PMC article.

7

Combined vaccine+axitinib therapy yields superior antitumor efficacy in a murine melanoma model.

Bose A, Lowe DB, Rao A, Storkus WJ. Bose A, et al. Melanoma Res. 2012 Jun;22(3):236-43. doi: 10.1097/CMR.0b013e3283538293. Melanoma Res. 2012. PMID: 22504156 Free PMC article.

8

Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma.

Lowe DB, Bose A, Taylor JL, Tawbi H, Lin Y, Kirkwood JM, Storkus WJ. Lowe DB, et al. Oncoimmunology. 2014 Jan 1;3(1):e27589. doi: 10.4161/onci.27589. Epub 2014 Feb 27. Oncoimmunology. 2014. PMID: 24734217 Free PMC article.

9

Shock block for improved immunotherapy.

Rao A, Lowe DB, Storkus WJ. Rao A, et al. Oncoimmunology. 2012 Nov 1;1(8):1427-1429. doi: 10.4161/onci.21174. Oncoimmunology. 2012. PMID: 23243617 Free PMC article.

10

Monitoring antigen-specific T cell responses using real-time PCR.

Lowe DB, Taylor JL, Storkus WJ. Lowe DB, et al. Methods Mol Biol. 2014;1186:65-74. doi: 10.1007/978-1-4939-1158-5_5. Methods Mol Biol. 2014. PMID: 25149303 Free PMC article.

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