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Imatinib can act as an Allosteric Activator of Abl Kinase.
Xie T, Saleh T, Rossi P, Miller D, Kalodimos CG. Xie T, et al. Among authors: miller d. J Mol Biol. 2022 Jan 30;434(2):167349. doi: 10.1016/j.jmb.2021.167349. Epub 2021 Nov 10. J Mol Biol. 2022. PMID: 34774565 Free PMC article.
Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Reshetnyak AV, Rossi P, Myasnikov AG, Sowaileh M, Mohanty J, Nourse A, Miller DJ, Lax I, Schlessinger J, Kalodimos CG. Reshetnyak AV, et al. Nature. 2021 Dec;600(7887):153-157. doi: 10.1038/s41586-021-04140-8. Epub 2021 Nov 24. Nature. 2021. PMID: 34819673 Free PMC article.
Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5.
Wang J, Buchman CD, Seetharaman J, Miller DJ, Huber AD, Wu J, Chai SC, Garcia-Maldonado E, Wright WC, Chenge J, Chen T. Wang J, et al. Among authors: miller dj. J Am Chem Soc. 2021 Nov 10;143(44):18467-18480. doi: 10.1021/jacs.1c07066. Epub 2021 Oct 14. J Am Chem Soc. 2021. PMID: 34648292 Free PMC article.
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