Rana S - Search Results

1

Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase.

Rana S, Mallareddy JR, Singh S, Boghean L, Natarajan A. Rana S, et al. Cancers (Basel). 2021 Nov 2;13(21):5506. doi: 10.3390/cancers13215506. Cancers (Basel). 2021. PMID: 34771669 Free PMC article. Review.

2

Face selective reduction of the exocyclic double bond in isatin derived spirocyclic lactones.

Rana S, Natarajan A. Rana S, et al. Org Biomol Chem. 2013 Jan 14;11(2):244-7. doi: 10.1039/c2ob27008k. Epub 2012 Nov 19. Org Biomol Chem. 2013. PMID: 23160888 Free PMC article.

3

Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase.

Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock B, Chorev M, Aktas BH. Chen T, et al. Among authors: rana s. J Med Chem. 2013 Dec 12;56(23):9457-70. doi: 10.1021/jm400793v. Epub 2013 Nov 27. J Med Chem. 2013. PMID: 24261904 Free PMC article.

4

Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.

Rana S, Blowers EC, Natarajan A. Rana S, et al. J Med Chem. 2015 Jan 8;58(1):2-29. doi: 10.1021/jm401994c. Epub 2014 Aug 28. J Med Chem. 2015. PMID: 25122135 Free PMC article. Review.

5

Irreversible binding of an anticancer compound (BI-94) to plasma proteins.

Gautam N, Thakare R, Rana S, Natarajan A, Alnouti Y. Gautam N, et al. Among authors: rana s. Xenobiotica. 2015;45(10):858-73. doi: 10.3109/00498254.2015.1025250. Epub 2015 Apr 14. Xenobiotica. 2015. PMID: 25869245 Free PMC article.

6

Micellar formulation of indocyanine green for phototherapy of melanoma.

Mundra V, Peng Y, Rana S, Natarajan A, Mahato RI. Mundra V, et al. Among authors: rana s. J Control Release. 2015 Dec 28;220(Pt A):130-140. doi: 10.1016/j.jconrel.2015.10.029. Epub 2015 Oct 19. J Control Release. 2015. PMID: 26482083

7

A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβ.

Maroni D, Rana S, Mukhopadhyay C, Natarajan A, Naramura M. Maroni D, et al. Among authors: rana s. Immunol Lett. 2015 Dec;168(2):319-24. doi: 10.1016/j.imlet.2015.10.011. Epub 2015 Oct 27. Immunol Lett. 2015. PMID: 26518140 Free PMC article.

8

Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy.

Sonawane YA, Taylor MA, Napoleon JV, Rana S, Contreras JI, Natarajan A. Sonawane YA, et al. Among authors: rana s. J Med Chem. 2016 Oct 13;59(19):8667-8684. doi: 10.1021/acs.jmedchem.6b00150. Epub 2016 Jun 3. J Med Chem. 2016. PMID: 27171036 Free PMC article.

9

Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response.

Yefidoff-Freedman R, Fan J, Yan L, Zhang Q, Dos Santos GRR, Rana S, Contreras JI, Sahoo R, Wan D, Young J, Dias Teixeira KL, Morisseau C, Halperin J, Hammock B, Natarajan A, Wang P, Chorev M, Aktas BH. Yefidoff-Freedman R, et al. Among authors: rana s. J Med Chem. 2017 Jul 13;60(13):5392-5406. doi: 10.1021/acs.jmedchem.7b00059. Epub 2017 Jun 19. J Med Chem. 2017. PMID: 28590739 Free PMC article.

10

Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC).

Robb CM, Contreras JI, Kour S, Taylor MA, Abid M, Sonawane YA, Zahid M, Murry DJ, Natarajan A, Rana S. Robb CM, et al. Among authors: rana s. Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580. doi: 10.1039/c7cc03879h. Chem Commun (Camb). 2017. PMID: 28636052 Free PMC article.

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