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Tetraspanin 5 (TSPAN5), a Novel Gatekeeper of the Tumor Suppressor DLC1 and Myocardin-Related Transcription Factors (MRTFs), Controls HCC Growth and Senescence.
Schreyer L, Mittermeier C, Franz MJ, Meier MA, Martin DE, Maier KC, Huebner K, Schneider-Stock R, Singer S, Holzer K, Fischer D, Ribback S, Liebl B, Gudermann T, Aigner A, Muehlich S. Schreyer L, et al. Among authors: muehlich s. Cancers (Basel). 2021 Oct 26;13(21):5373. doi: 10.3390/cancers13215373. Cancers (Basel). 2021. PMID: 34771537 Free PMC article.
Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence.
Hampl V, Martin C, Aigner A, Hoebel S, Singer S, Frank N, Sarikas A, Ebert O, Prywes R, Gudermann T, Muehlich S. Hampl V, et al. Among authors: muehlich s. EMBO Mol Med. 2013 Sep;5(9):1367-82. doi: 10.1002/emmm.201202406. Epub 2013 Jul 29. EMBO Mol Med. 2013. PMID: 23853104 Free PMC article.
Pro-senescence therapy for hepatocellular carcinoma.
Muehlich S, Gudermann T. Muehlich S, et al. Aging (Albany NY). 2013 Sep;5(9):639-40. doi: 10.18632/aging.100601. Aging (Albany NY). 2013. PMID: 24057649 Free PMC article. No abstract available.
The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.
Hermanns C, Hampl V, Holzer K, Aigner A, Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S. Hermanns C, et al. Among authors: muehlich s. Oncogene. 2017 Jun 15;36(24):3464-3476. doi: 10.1038/onc.2016.496. Epub 2017 Jan 23. Oncogene. 2017. PMID: 28114277
TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut.
Romagnani A, Vettore V, Rezzonico-Jost T, Hampe S, Rottoli E, Nadolni W, Perotti M, Meier MA, Hermanns C, Geiger S, Wennemuth G, Recordati C, Matsushita M, Muehlich S, Proietti M, Chubanov V, Gudermann T, Grassi F, Zierler S. Romagnani A, et al. Among authors: muehlich s. Nat Commun. 2017 Dec 4;8(1):1917. doi: 10.1038/s41467-017-01960-z. Nat Commun. 2017. PMID: 29203869 Free PMC article.
Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity.
Voringer S, Schreyer L, Nadolni W, Meier MA, Woerther K, Mittermeier C, Ferioli S, Singer S, Holzer K, Zierler S, Chubanov V, Liebl B, Gudermann T, Muehlich S. Voringer S, et al. Among authors: muehlich s. Oncogene. 2020 Mar;39(11):2328-2344. doi: 10.1038/s41388-019-1140-8. Epub 2019 Dec 16. Oncogene. 2020. PMID: 31844251
25 results