Aigner A - Search Results

1

Tetraspanin 5 (TSPAN5), a Novel Gatekeeper of the Tumor Suppressor DLC1 and Myocardin-Related Transcription Factors (MRTFs), Controls HCC Growth and Senescence.

Schreyer L, Mittermeier C, Franz MJ, Meier MA, Martin DE, Maier KC, Huebner K, Schneider-Stock R, Singer S, Holzer K, Fischer D, Ribback S, Liebl B, Gudermann T, Aigner A, Muehlich S. Schreyer L, et al. Among authors: aigner a. Cancers (Basel). 2021 Oct 26;13(21):5373. doi: 10.3390/cancers13215373. Cancers (Basel). 2021. PMID: 34771537 Free PMC article.

2

Delivery of unmodified bioactive ribozymes by an RNA-stabilizing polyethylenimine (LMW-PEI) efficiently down-regulates gene expression.

Aigner A, Fischer D, Merdan T, Brus C, Kissel T, Czubayko F. Aigner A, et al. Gene Ther. 2002 Dec;9(24):1700-7. doi: 10.1038/sj.gt.3301839. Gene Ther. 2002. PMID: 12457284

3

Critical role of G(alpha)12 and G(alpha)13 for human small cell lung cancer cell proliferation in vitro and tumor growth in vivo.

Grzelinski M, Pinkenburg O, Büch T, Gold M, Stohr S, Kalwa H, Gudermann T, Aigner A. Grzelinski M, et al. Among authors: aigner a. Clin Cancer Res. 2010 Mar 1;16(5):1402-15. doi: 10.1158/1078-0432.CCR-09-1873. Epub 2010 Feb 16. Clin Cancer Res. 2010. PMID: 20160064

4

Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells.

Schaefer EA, Stohr S, Meister M, Aigner A, Gudermann T, Buech TR. Schaefer EA, et al. Among authors: aigner a. Biochem Pharmacol. 2013 Feb 1;85(3):426-38. doi: 10.1016/j.bcp.2012.11.019. Epub 2012 Dec 5. Biochem Pharmacol. 2013. PMID: 23219522

5

Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence.

Hampl V, Martin C, Aigner A, Hoebel S, Singer S, Frank N, Sarikas A, Ebert O, Prywes R, Gudermann T, Muehlich S. Hampl V, et al. Among authors: aigner a. EMBO Mol Med. 2013 Sep;5(9):1367-82. doi: 10.1002/emmm.201202406. Epub 2013 Jul 29. EMBO Mol Med. 2013. PMID: 23853104 Free PMC article.

6

A novel method for the assessment of targeted PEI-based nanoparticle binding based on a static surface plasmon resonance system.

Höbel S, Vornicescu D, Bauer M, Fischer D, Keusgen M, Aigner A. Höbel S, et al. Among authors: aigner a. Anal Chem. 2014 Jul 15;86(14):6827-35. doi: 10.1021/ac402001q. Epub 2013 Nov 20. Anal Chem. 2014. PMID: 24191676

7

Nanoparticle-mediated delivery of small RNA molecules in tumor therapy.

Aigner A, Fischer D. Aigner A, et al. Pharmazie. 2016 Jan;71(1):27-34. Pharmazie. 2016. PMID: 26867350 Review.

8

The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.

Hermanns C, Hampl V, Holzer K, Aigner A, Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S. Hermanns C, et al. Among authors: aigner a. Oncogene. 2017 Jun 15;36(24):3464-3476. doi: 10.1038/onc.2016.496. Epub 2017 Jan 23. Oncogene. 2017. PMID: 28114277

9

Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model.

Linder B, Weirauch U, Ewe A, Uhmann A, Seifert V, Mittelbronn M, Harter PN, Aigner A, Kögel D. Linder B, et al. Among authors: aigner a. Cancers (Basel). 2019 Mar 8;11(3):333. doi: 10.3390/cancers11030333. Cancers (Basel). 2019. PMID: 30857197 Free PMC article.

10

Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives.

Jenke R, Reßing N, Hansen FK, Aigner A, Büch T. Jenke R, et al. Among authors: aigner a. Cancers (Basel). 2021 Feb 5;13(4):634. doi: 10.3390/cancers13040634. Cancers (Basel). 2021. PMID: 33562653 Free PMC article. Review.

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