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Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway.
Klein W, Rutz C, Eckhard J, Provinciael B, Specker E, Neuenschwander M, Kleinau G, Scheerer P, von Kries JP, Nazaré M, Vermeire K, Schülein R. Klein W, et al. Among authors: vermeire k. PLoS One. 2018 Dec 13;13(12):e0208641. doi: 10.1371/journal.pone.0208641. eCollection 2018. PLoS One. 2018. PMID: 30543669 Free PMC article.
Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds.
Berger K, Pauwels E, Parkinson G, Landberg G, Le T, Demillo VG, Lumangtad LA, Jones DE, Islam MA, Olsen R, Kapri T, Intasiri A, Vermeire K, Rhost S, Bell TW. Berger K, et al. Among authors: vermeire k. J Med Chem. 2021 Sep 9;64(17):12865-12876. doi: 10.1021/acs.jmedchem.1c00943. Epub 2021 Aug 24. J Med Chem. 2021. PMID: 34428050 Free PMC article.
A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide.
Pauwels E, Rutz C, Provinciael B, Stroobants J, Schols D, Hartmann E, Krause E, Stephanowitz H, Schülein R, Vermeire K. Pauwels E, et al. Among authors: vermeire k. Mol Cell Proteomics. 2021;20:100144. doi: 10.1016/j.mcpro.2021.100144. Epub 2021 Sep 2. Mol Cell Proteomics. 2021. PMID: 34481949 Free PMC article.
139 results