Mahgoub S - Search Results

1

Synthesis of Novel 2-Thiouracil-5-Sulfonamide Derivatives as Potent Inducers of Cell Cycle Arrest and CDK2A Inhibition Supported by Molecular Docking.

Fatahala SS, Sayed AI, Mahgoub S, Taha H, El-Sayed MK, El-Shehry MF, Awad SM, Abd El-Hameed RH. Fatahala SS, et al. Among authors: mahgoub s. Int J Mol Sci. 2021 Nov 4;22(21):11957. doi: 10.3390/ijms222111957. Int J Mol Sci. 2021. PMID: 34769385 Free PMC article.

2

Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Thiouracil Derivatives as Potential Antithyroid Agents.

Awad SM, Zohny YM, Ali SA, Mahgoub S, Said AM. Awad SM, et al. Among authors: mahgoub s. Molecules. 2018 Nov 8;23(11):2913. doi: 10.3390/molecules23112913. Molecules. 2018. PMID: 30413058 Free PMC article.

3

Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors.

Ali SA, Awad SM, Said AM, Mahgoub S, Taha H, Ahmed NM. Ali SA, et al. Among authors: mahgoub s. J Enzyme Inhib Med Chem. 2020 Dec;35(1):847-863. doi: 10.1080/14756366.2020.1742116. J Enzyme Inhib Med Chem. 2020. PMID: 32216479 Free PMC article.

4

Green Coffea arabica Extract Ameliorates Testicular Injury in High-Fat Diet/Streptozotocin-Induced Diabetes in Rats.

Al-Megrin WA, El-Khadragy MF, Hussein MH, Mahgoub S, Abdel-Mohsen DM, Taha H, Bakkar AAA, Abdel Moneim AE, Amin HK. Al-Megrin WA, et al. Among authors: mahgoub s. J Diabetes Res. 2020 Jun 12;2020:6762709. doi: 10.1155/2020/6762709. eCollection 2020. J Diabetes Res. 2020. PMID: 32626781 Free PMC article.

5

Biphenylurea/thiourea derivatives tagged with heteroarylsulfonamide motifs as novel VEGFR2 inhibitors; Design, synthesis and anti-angiogenic activity.

Al-Ansary GH, Nasr T, Taha H, Fayad W, Mahgoub S. Al-Ansary GH, et al. Among authors: mahgoub s. Bioorg Chem. 2021 Feb;107:104640. doi: 10.1016/j.bioorg.2021.104640. Epub 2021 Jan 11. Bioorg Chem. 2021. PMID: 33485105

6

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition.

Abd El-Hameed RH, Mahgoub S, El-Shanbaky HM, Mohamed MS, Ali SA. Abd El-Hameed RH, et al. Among authors: mahgoub s. J Enzyme Inhib Med Chem. 2021 Dec;36(1):977-986. doi: 10.1080/14756366.2021.1908277. J Enzyme Inhib Med Chem. 2021. PMID: 33957835 Free PMC article.

7

Synthesis of novel calcium channel blockers with ACE2 inhibition and dual antihypertensive/anti-inflammatory effects: A possible therapeutic tool for COVID-19.

Mahgoub S, Kotb El-Sayed MI, El-Shehry MF, Mohamed Awad S, Mansour YE, Fatahala SS. Mahgoub S, et al. Bioorg Chem. 2021 Nov;116:105272. doi: 10.1016/j.bioorg.2021.105272. Epub 2021 Aug 24. Bioorg Chem. 2021. PMID: 34474305 Free PMC article.

8

Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19.

Mahgoub S, Fatahala SS, Sayed AI, Atya HB, El-Shehry MF, Afifi H, Awad SM, El-Hameed RHA, Taha H. Mahgoub S, et al. Bioorg Chem. 2022 Nov;128:106092. doi: 10.1016/j.bioorg.2022.106092. Epub 2022 Aug 10. Bioorg Chem. 2022. PMID: 35985159 Free PMC article.

9

Polyphenolic Profile of Callistemon viminalis Aerial Parts: Antioxidant, Anticancer and In Silico 5-LOX Inhibitory Evaluations.

Mahgoub S, Hashad N, Ali S, Ibrahim R, Said AM, Moharram FA, Mady M. Mahgoub S, et al. Molecules. 2021 Apr 24;26(9):2481. doi: 10.3390/molecules26092481. Molecules. 2021. PMID: 33923148 Free PMC article.

10

Restoring NK cells functionality via cytokine activation enhances cetuximab-mediated NK-cell ADCC: A promising therapeutic tool for HCC patients.

Mahgoub S, Abosalem H, Emara M, Kotb N, Maged A, Soror S. Mahgoub S, et al. Mol Immunol. 2021 Sep;137:221-227. doi: 10.1016/j.molimm.2021.07.008. Epub 2021 Jul 17. Mol Immunol. 2021. PMID: 34284214

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