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Nicotinamide for the treatment of heart failure with preserved ejection fraction.
Abdellatif M, Trummer-Herbst V, Koser F, Durand S, Adão R, Vasques-Nóvoa F, Freundt JK, Voglhuber J, Pricolo MR, Kasa M, Türk C, Aprahamian F, Herrero-Galán E, Hofer SJ, Pendl T, Rech L, Kargl J, Anto-Michel N, Ljubojevic-Holzer S, Schipke J, Brandenberger C, Auer M, Schreiber R, Koyani CN, Heinemann A, Zirlik A, Schmidt A, von Lewinski D, Scherr D, Rainer PP, von Maltzahn J, Mühlfeld C, Krüger M, Frank S, Madeo F, Eisenberg T, Prokesch A, Leite-Moreira AF, Lourenço AP, Alegre-Cebollada J, Kiechl S, Linke WA, Kroemer G, Sedej S. Abdellatif M, et al. Among authors: kruger m. Sci Transl Med. 2021 Feb 10;13(580):eabd7064. doi: 10.1126/scitranslmed.abd7064. Sci Transl Med. 2021. PMID: 33568522 Free PMC article.
Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Sen A, Kallabis S, Gaedke F, Jüngst C, Boix J, Nüchel J, Maliphol K, Hofmann J, Schauss AC, Krüger M, Wiesner RJ, Pla-Martín D. Sen A, et al. Among authors: kruger m. Nat Commun. 2022 Nov 7;13(1):6704. doi: 10.1038/s41467-022-34205-9. Nat Commun. 2022. PMID: 36344526 Free PMC article.
Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage.
Bubb K, Holzer T, Nolte JL, Krüger M, Wilson R, Schlötzer-Schrehardt U, Brinckmann J, Altmüller J, Aszodi A, Fleischhauer L, Clausen-Schaumann H, Probst K, Brachvogel B. Bubb K, et al. Among authors: kruger m. J Biol Chem. 2021 Oct;297(4):101224. doi: 10.1016/j.jbc.2021.101224. Epub 2021 Sep 22. J Biol Chem. 2021. PMID: 34560099 Free PMC article.
Deubiquitinase USP10 regulates Notch signaling in the endothelium.
Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I, Potente M. Lim R, et al. Among authors: kruger m. Science. 2019 Apr 12;364(6436):188-193. doi: 10.1126/science.aat0778. Science. 2019. PMID: 30975888
Organ Protection by Caloric Restriction Depends on Activation of the De Novo NAD+ Synthesis Pathway.
Späth MR, Hoyer-Allo KJR, Seufert L, Höhne M, Lucas C, Bock T, Isermann L, Brodesser S, Lackmann JW, Kiefer K, Koehler FC, Bohl K, Ignarski M, Schiller P, Johnsen M, Kubacki T, Grundmann F, Benzing T, Trifunovic A, Krüger M, Schermer B, Burst V, Müller RU. Späth MR, et al. Among authors: kruger m. J Am Soc Nephrol. 2023 May 1;34(5):772-792. doi: 10.1681/ASN.0000000000000087. Epub 2023 Feb 9. J Am Soc Nephrol. 2023. PMID: 36758124 Free PMC article.
1,623 results