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Page 1
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1.
Fiorillo B, Sepe V, Conflitti P, Roselli R, Biagioli M, Marchianò S, De Luca P, Baronissi G, Rapacciuolo P, Cassiano C, Catalanotti B, Zampella A, Limongelli V, Fiorucci S. Fiorillo B, et al. Among authors: roselli r. J Med Chem. 2021 Nov 25;64(22):16512-16529. doi: 10.1021/acs.jmedchem.1c01078. Epub 2021 Nov 12. J Med Chem. 2021. PMID: 34767347
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis.
Biagioli M, Carino A, Fiorucci C, Marchianò S, Di Giorgio C, Roselli R, Magro M, Distrutti E, Bereshchenko O, Scarpelli P, Zampella A, Fiorucci S. Biagioli M, et al. Among authors: roselli r. Cell Mol Gastroenterol Hepatol. 2019;8(3):447-473. doi: 10.1016/j.jcmgh.2019.06.003. Epub 2019 Jun 18. Cell Mol Gastroenterol Hepatol. 2019. PMID: 31226434 Free PMC article.
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions.
Biagioli M, Carino A, Fiorucci C, Annunziato G, Marchianò S, Bordoni M, Roselli R, Giorgio CD, Castiglione F, Ricci P, Bruno A, Faccini A, Distrutti E, Baldoni M, Costantino G, Fiorucci S. Biagioli M, et al. Among authors: roselli r. Nutrients. 2019 Aug 7;11(8):1820. doi: 10.3390/nu11081820. Nutrients. 2019. PMID: 31394746 Free PMC article.
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
Carino A, Biagioli M, Marchianò S, Fiorucci C, Bordoni M, Roselli R, Di Giorgio C, Baldoni M, Ricci P, Monti MC, Morretta E, Zampella A, Distrutti E, Fiorucci S. Carino A, et al. Among authors: roselli r. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158733. doi: 10.1016/j.bbalip.2020.158733. Epub 2020 May 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32371093
GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis.
Marino S, Finamore C, Biagioli M, Carino A, Marchianò S, Roselli R, Giorgio CD, Bordoni M, Di Leva FS, Novellino E, Cassiano C, Limongelli V, Zampella A, Festa C, Fiorucci S. Marino S, et al. Among authors: roselli r. ACS Med Chem Lett. 2020 Mar 2;11(5):818-824. doi: 10.1021/acsmedchemlett.9b00636. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435390 Free PMC article.
140 results