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Page 1
Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes.
Dall M, Hassing AS, Niu L, Nielsen TS, Ingerslev LR, Sulek K, Trammell SAJ, Gillum MP, Barrès R, Larsen S, Poulsen SS, Mann M, Ørskov C, Treebak JT. Dall M, et al. Among authors: treebak jt. J Biol Chem. 2021 Dec;297(6):101388. doi: 10.1016/j.jbc.2021.101388. Epub 2021 Nov 8. J Biol Chem. 2021. PMID: 34762911 Free PMC article.
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes.
Moltke I, Grarup N, Jørgensen ME, Bjerregaard P, Treebak JT, Fumagalli M, Korneliussen TS, Andersen MA, Nielsen TS, Krarup NT, Gjesing AP, Zierath JR, Linneberg A, Wu X, Sun G, Jin X, Al-Aama J, Wang J, Borch-Johnsen K, Pedersen O, Nielsen R, Albrechtsen A, Hansen T. Moltke I, et al. Among authors: treebak jt. Nature. 2014 Aug 14;512(7513):190-3. doi: 10.1038/nature13425. Epub 2014 Jun 18. Nature. 2014. PMID: 25043022
Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet.
Penke M, Larsen PS, Schuster S, Dall M, Jensen BA, Gorski T, Meusel A, Richter S, Vienberg SG, Treebak JT, Kiess W, Garten A. Penke M, et al. Among authors: treebak jt. Mol Cell Endocrinol. 2015 Sep 5;412:65-72. doi: 10.1016/j.mce.2015.05.028. Epub 2015 May 29. Mol Cell Endocrinol. 2015. PMID: 26033245
Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain.
Jensen BA, Nielsen TS, Fritzen AM, Holm JB, Fjære E, Serup AK, Borkowski K, Risis S, Pærregaard SI, Søgaard I, Poupeau A, Poulsen M, Ma T, Sina C, Kiens B, Madsen L, Kristiansen K, Treebak JT. Jensen BA, et al. Among authors: treebak jt. Metabolism. 2016 Dec;65(12):1706-1719. doi: 10.1016/j.metabol.2016.09.002. Epub 2016 Sep 12. Metabolism. 2016. PMID: 27832859 Free article.
Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle.
Agerholm M, Dall M, Jensen BAH, Prats C, Madsen S, Basse AL, Graae AS, Risis S, Goldenbaum J, Quistorff B, Larsen S, Vienberg SG, Treebak JT. Agerholm M, et al. Among authors: treebak jt. Am J Physiol Endocrinol Metab. 2018 Apr 1;314(4):E377-E395. doi: 10.1152/ajpendo.00213.2017. Epub 2017 Dec 5. Am J Physiol Endocrinol Metab. 2018. PMID: 29208611 Free article.
Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model.
Reynolds RH, Petersen MH, Willert CW, Heinrich M, Nymann N, Dall M, Treebak JT, Björkqvist M, Silahtaroglu A, Hasholt L, Nørremølle A. Reynolds RH, et al. Among authors: treebak jt. Mol Cell Neurosci. 2018 Apr;88:118-129. doi: 10.1016/j.mcn.2017.12.009. Epub 2017 Dec 28. Mol Cell Neurosci. 2018. PMID: 29289683
116 results